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Keywords: Polymorphism
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Biosci Rep (2021) 41 (4): BSR20210522.
Published: 22 April 2021
...Feifei Jiang; Aihui Yan Objective: The relationship between IL-4 rs2243250 polymorphism and the risk of allergic rhinitis is not clear at present. The present study aims to evaluate the exact association between IL-4 rs2243250 polymorphism and susceptibility to allergic rhinitis by a meta-analysis...
Includes: Supplementary data
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Biosci Rep (2021) 41 (2): BSR20201158.
Published: 17 February 2021
... nucleotide polymorphisms (SNPs) genotypic distributions were different in NSCLC cases and controls. However, the association of miR-196a-2 rs11614913 with a decreased risk of NSCLC was identified in the female subgroup (adjusted P =0.005, power = 0.809 for TC vs. TT, and adjusted P =0.004, power = 0.849...
Includes: Supplementary data
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Biosci Rep (2021) 41 (2): BSR20193877.
Published: 03 February 2021
...Bi-jun Wang; Jun-yi Chen; Yu Guan; Da-chao Liu; Zi-chuan Cao; Jin Kong; Zheng-Sheng Wu; Wen-Yong Wu Background: Both meta-analyses and systematic reviews were used to assess the relationship between purinergic receptor P2X ligand-gated ion channel 7 ( P2RX7 ) rs3751143 polymorphism and the risk...
Includes: Supplementary data
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Biosci Rep (2021) 41 (1): BSR20203461.
Published: 06 January 2021
...Guoxiang Rong; Yongping Zhu; Weifeng Tang; Hao Qiu; Sheng Zhang The relationship between rs3746444 T>C single-nucleotide polymorphism (SNP) in microRNA (mir)-499 and risk of gastric cancer (GC) has been widely investigated. However, the association was still unconfirmed. Here, we first recruited...
Includes: Supplementary data
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Biosci Rep (2021) 41 (1): BSR20191729.
Published: 04 January 2021
..., 7947 CRC cases and 12,168 controls were included. We found that miR-146a rs2910164 polymorphism did not influence the risk of CRC (G vs. C: P =0.537; GG vs. CC: P =0.517, CG/GG vs. CC: P =0.520 and GG vs. CC/CG: P =0.167). Our findings suggest that miR-146a rs2910164 C/G polymorphism is not correlated...
Includes: Supplementary data
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Biosci Rep (2020) 40 (9): BSR20200027.
Published: 16 September 2020
...Yue-e Wu; Lan Ma; Hao Zhang; Xin-ran Chen; Xin-yi Xu; Ze-ping Hu Several studies have investigated a potential association between the endothelial lipase gene ( LIPG ) 584C/T polymorphism and susceptibility to coronary artery disease (CAD), but a uniform conclusion is yet to be reached. To better...
Includes: Supplementary data
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Biosci Rep (2020) 40 (7): BSR20200068.
Published: 21 July 2020
... = 1.04–1.52, P =0.02) and was a genetic biomarker of severe manifestations after surgery. These findings indicate that the rs9690350 G allele is a PDGFA polymorphism associated with the risk of BA that may confer increased disease susceptibility. Correspondence: Ruizhong Zhang ( cowboy2006@163.com...
Includes: Supplementary data
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Biosci Rep (2020) 40 (7): BSR20191825.
Published: 09 July 2020
...Guang-Hui Qi; Chun-Hui Wang; Hong-Ge Zhang; Jian-Guo Yu; Fei Ding; Zhi-Chao Song; Qing-Hua Xia There is still no conclusion on the potential effect of the rs2295080 and rs2536 polymorphisms of mTOR (mammalian target of rapamycin) gene on different cancers. Herein, we performed a comprehensive...
Includes: Supplementary data
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Biosci Rep (2020) 40 (7): BSR20192313.
Published: 02 July 2020
...Ahu Soyocak; Merih Özgen; Didem Turgut Coşan; Hülyam Kurt; Fulya Doğaner; Onur Armağan; İrfan Değirmenci; Fezan Şahin Mutlu The present study was aimed to investigate the relationship between NOD1/CARD4 and NOD2/CARD15 gene polymorphisms and osteoporosis in the Turkish population. The first time we...
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Biosci Rep (2020) 40 (6): BSR20192410.
Published: 26 June 2020
...Li-Fang Wu; Gui-Ping Xu; Qing Zhao; Ding Wang; Li-Jing Zhou; Bin Sun; Wei-Xian Chen Background: The evidence for an association between the adiponectin gene (ADIPOQ) polymorphism rs182052 and cancer risk is inconsistent. We performed a meta-analysis to obtain more precise conclusions. Methods...
Includes: Supplementary data
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Biosci Rep (2020) 40 (6): BSR20193779.
Published: 05 June 2020
... 6p24.1 (rs1223397, P =1.04e −07 ). The purpose of the present study was to investigate associations of PHACTR1 gene polymorphisms with PP in a Chinese population. We recruited 347 subjects with PP ≥ 65 mmHg as cases and 359 subjects with 30 ≤ PP ≤ 45 mmHg as controls. Seven single nucleotide...
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Biosci Rep (2020) 40 (5): BSR20190629.
Published: 14 May 2020
...Anum Zehra Naqvi; Ishrat Mahjabeen; Saima Ameen; Malik Waqar Ahmed; Asad Ullah Khan; Zertashia Akram; Mahmood Akhtar Kayani The present study was designed to determine the association between the genetic polymorphisms/expression variations of RB1 and CCND1 genes and brain tumor risk...
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Biosci Rep (2020) 40 (5): BSR20193989.
Published: 11 May 2020
...Yi Zheng; Tongyi Lu; Xiaoli Xie; Qiuming He; Lifeng Lu; Wei Zhong MicroRNAs (miRNAs) are endogenous non-coding small RNAs that play an important role in the development of many malignant tumors. In addition, recent studies have reported that single nucleotide polymorphisms (SNPs) located...
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Biosci Rep (2020) 40 (5): BSR20191188.
Published: 05 May 2020
... to the patient, affecting speech, swallowing and respiratory skills. Smoking and alcohol abuse are principal risk factors linked to this disease. Genetic factors can be involved in carcinogenesis by controlling the cell cycle, cell survival, angiogenesis, and invasiveness. Single nucleotide polymorphisms (SNPs...
Includes: Supplementary data
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Biosci Rep (2020) 40 (4): BSR20200406.
Published: 09 April 2020
...Qianqian Yu; Jing Zhu; Yong Yao; Chao Sun The complement factor I ( CFI ) gene polymorphisms have been reported to age-related macular degenerative (AMD) risk, nevertheless, above association is not consistent. We investigated a meta-analysis to evaluate the conclusions between CFI polymorphisms...
Includes: Supplementary data
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Biosci Rep (2020) 40 (3): BSR20191691.
Published: 13 March 2020
...Li Huang; Lunwen Wang Vascular endothelial growth factor ( VEGF ) plays a critical role in ovarian folliculogenesis and normal reproductive function. So far, several studies focusing on association between VEGF gene polymorphisms and polycystic ovary syndrome (PCOS). However, above association...
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Biosci Rep (2020) 40 (2): BSR20194202.
Published: 28 February 2020
... of TP53 mutations, the methylation of miR34b/c , and the interaction between these two molecules in tumorigenesis have been well documented. Due to the biological connection between p53 and miR34b/c , in the present study, we investigated the association between polymorphisms in these two molecules...
Includes: Supplementary data
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Biosci Rep (2020) 40 (1): BSR20191449.
Published: 06 January 2020
...Menglei Yu; Jingyi Hou; Minghui Zheng; Yi Cao; Yamuhanmode Alike; Yuanyuan Mi; Jie Zhu Interleukin-21 (IL-21) is a cytokine that plays a crucial role in pathogenesis and activity of the rheumatoid arthritis (RA). Meanwhile, genetic polymorphisms in the IL-21 gene may alter its expression. Previous...
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Biosci Rep (2019) 39 (12): BSR20191770.
Published: 13 December 2019
...Weifeng Tang; Shuchen Chen; Mingqiang Kang; Jun Liu; Chao Liu Background: Variants in B- and T-lymphocyte attenuator ( BTLA ) gene are likely to affect the function of BTLA protein. Methods: In the present case–control study, we selected BTLA tagging single-nucleotide polymorphisms (SNPs...
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Biosci Rep (2019) 39 (10): BSR20191549.
Published: 21 October 2019
...Kaisong Miao; Lifeng Jiang; Xindie Zhou; Lidong Wu; Yong Huang; Nanwei Xu; Junjie Zhang; Jin Li An association of Matrix Metalloproteinases-1/3 (MMP-1/3) rs1799750/rs3025058 polymorphism with increased risk of rotator cuff tear (RCT) has been reported in a Brazilian population. However...
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Biosci Rep (2019) 39 (10): BSR20192529.
Published: 18 October 2019
... life. The association between PHOX2B single nucleotide polymorphisms (SNPs) and Wilms tumor risk has not been investigated. Therefore, we conducted a case-control study involving 145 Wilms tumor patients and 531 controls to explore the association between the PHOX2B rs28647582 T>C polymorphism...
Includes: Supplementary data
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Biosci Rep (2019) 39 (9): BSR20181025.
Published: 03 September 2019
...Kangpeng Yan; Kun Wu; Chao Lin; Zhigang Jie Previous studies have identified the prostate stem cell antigen ( PSCA ) gene rs2294008 C > T and rs2976392 G > A polymorphisms to be associated with the risk of gastric cancer, the results of which are inconsistent. The present study aimed...
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Biosci Rep (2019) 39 (8): BSR20190741.
Published: 23 August 2019
...Xingliang Feng; Dan Ji; Chaozhao Liang; Song Fan Piles of evidence have supported the relationship between miR-618 rs2682818 polymorphism and tumorigenesis, but the conclusion remains inconsistent. In the present study, we conducted a meta-analysis to sniff out the potential risk between miR-618...
Includes: Supplementary data