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Keywords: PI3K/AKT pathway
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Articles
Biosci Rep (2021) 41 (12): BSR20192007.
Published: 08 December 2021
... and apoptosis rate when cisplatin was added in HCC cells. In contrast, knockdown of miR-27a-3p significantly showed an opposite trend. In addition, Western blot revealed that miR-27a-3p plus cisplatin revealed weaker expressions of PI3K and p-Akt and stronger level of C-caspase-3. Thus, PI3K/Akt pathway...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (6): BSR20210477.
Published: 21 June 2021
..., the results suggest that TMJ-12 prevents BPH-1 cell proliferation via the PI3K/AKT pathway by inducing apoptosis and cell cycle arrest. Correspondence: Jianguo Zhu ( zhujianguodoctor@163.com ) or Yanmei Li ( liyanmei518@hotmail.com ) or Chen Yan ( 12992636@qq.com ) 03 03 2021 01 06 2021...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (6): BSR20210093.
Published: 10 June 2021
...Yonggang Xu; Rong Fang; Jie Shao; Zihao Cai Background: Triple-negative breast cancer (TNBC) is a refractory subtype of breast cancer, 25–30% of which have dysregulation in the PI3K/AKT pathway. The present study investigated the anticancer effect of erianin on TNBC cell line and its underlying...
Articles
Biosci Rep (2021) 41 (4): BSR-20182476_EOC.
Published: 06 April 2021
... PI3K/AKT pathway The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates. ...
Articles
Biosci Rep (2020) 40 (11): BSR20201870.
Published: 02 November 2020
... patients was analyzed by Chi-square test. NSCLC cells, and cell proliferation, cell apoptosis and expression of PI3K/Akt pathway-related proteins were detected by CCK-8 assay, cell apoptosis assay and Western blot, respectively. Results: HAND2-AS1 expression was significantly down-regulated in NSCLC. HAND2...
Articles
Biosci Rep (2020) 40 (3): BSR-20182466_RET.
Published: 13 March 2020
... © 2020 The Author(s). 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Hepatocellular carcinoma MiR-367 PTEN PI3K/AKT pathway Bioscience...
Articles
Biosci Rep (2019) 39 (11): BSR20190295.
Published: 15 November 2019
... duck myoblast proliferation via PI3K/Akt pathway. Correspondence: Jiwen Wang ( wjw2886166@163.com ) 07 02 2019 23 09 2019 17 10 2019 28 10 2019 © 2019 The Author(s). 2019 This is an open access article published by Portland Press Limited on behalf of the Biochemical...
Articles
Biosci Rep (2019) BSR20182466.
Published: 20 September 2019
...Zhihua Wang; Yu Luo The study aimed to investigate the functional roles of micorRNA (miR)-367 in progression of hepatocellular carcinoma (HCC), as well as its regulation on PI3K/AKT pathway. The relative expression of miR-367 in HCC tissues and cell line was detected using quantitative real-time...
Articles
Biosci Rep (2019) 39 (7): BSR20182476.
Published: 05 July 2019
... promoted the proliferation, migration, and invasion of OSCC cells, while its knockout could inhibit malignant behaviors of OSCC cells ( P <0.05). Excessive activation of PAR-2 enhanced phosphorylation level of PI3K, AKT, and mTOR revealing the activation of PI3K/AKT pathway. Moreover, LY294002...
Articles
Biosci Rep (2018) 38 (6): BSR20180741.
Published: 21 December 2018
... PI3K/AKT pathway and VEGF expression. Correspondence: Yonghong Dong ( cj1cwp5r@yeah.net ) 12 05 2018 07 06 2018 11 06 2018 13 06 2018 © 2018 The Author(s). 2018 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society...