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Keywords: Non-small cell lung cancer
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Articles

Retraction: Upregulated circular RNA VANGL1 contributes to progression of non-small cell lung cancer through inhibition of miR-195 and activation of Bcl-2

Journal: Bioscience Reports
Biosci Rep (2022) 42 (12): BSR-2018-2433_RET.
DOI: https://doi.org/10.1042/BSR-2018-2433_RET
Published: 22 December 2022
... © 2022 The Author(s). 2022 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . apoptosis circular RNA VANGL1 non-small cell lung cancer This article...
View article titled, Retraction: Upregulated circular RNA VANGL1 contributes to progression of <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span> through inhibition of miR-195 and activation of Bcl-2
Click here to open pdf in another window PDF for Retraction: Upregulated circular RNA VANGL1 contributes to progression of <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span> through inhibition of miR-195 and activation of Bcl-2
Articles

Identification and validation of a genomic mutation signature as a predictor for immunotherapy in NSCLC

Zemin Wang, You Ge, Han Li, Gaoqiang Fei, Shuai Wang, Pingmin Wei
Journal: Bioscience Reports
Biosci Rep (2022) 42 (11): BSR20220892.
DOI: https://doi.org/10.1042/BSR20220892
Published: 25 November 2022
... recognized as well. However, the evidence about non-small cell lung cancer (NSCLC) remains limited. We analyzed 310 immunotherapy patients with NSCLC from the Memorial Sloan Kettering Cancer Center (MSKCC) cohort. Lasso Cox regression was used to construct a GMS, and the prognostic value of GMS could be able...
View article titled, Identification and validation of a genomic mutation signature as a predictor for immunotherapy in NSCLC
Click here to open pdf in another window PDF for Identification and validation of a genomic mutation signature as a predictor for immunotherapy in NSCLC
Articles

Retraction: Long noncoding RNA HOXA-AS2 promotes non-small cell lung cancer progression by regulating miR-520a-3p

Journal: Bioscience Reports
Biosci Rep (2022) 42 (10): BSR-2019-0283_RET.
DOI: https://doi.org/10.1042/BSR-2019-0283_RET
Published: 07 October 2022
... with the Retraction. © 2022 The Author(s). 2022 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . HOXA-AS2 Long non-coding RNA miR-520a-3p non-small cell lung cancer...
View article titled, Retraction: Long noncoding RNA HOXA-AS2 promotes <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span> progression by regulating miR-520a-3p
Click here to open pdf in another window PDF for Retraction: Long noncoding RNA HOXA-AS2 promotes <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span> progression by regulating miR-520a-3p
Articles

Expression of Concern: Long noncoding RNA HOXA-AS2 promotes non-small cell lung cancer progression by regulating miR-520a-3p

Journal: Bioscience Reports
Biosci Rep (2022) 42 (7): BSR-2019-0283_EOC.
DOI: https://doi.org/10.1042/BSR-2019-0283_EOC
Published: 15 July 2022
... HOXA-AS2 Long non-coding RNA miR-520a-3p non-small cell lung cancer proliferation The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an Expression of Concern to notify readers whilst the Editorial Office...
View article titled, Expression of Concern: Long noncoding RNA HOXA-AS2 promotes <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span> progression by regulating miR-520a-3p
Click here to open pdf in another window PDF for Expression of Concern: Long noncoding RNA HOXA-AS2 promotes <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span> progression by regulating miR-520a-3p
Articles

USP52 inhibits cell proliferation by stabilizing PTEN protein in non-small cell lung cancer

Maoshu Zhu, Hui Zhang, Fuhua Lu, Zhaowei Wang, Yulong Wu, Huoshu Chen, Xin Fan, Zhijiang Yin, Fulong Liang
Journal: Bioscience Reports
Biosci Rep (2021) 41 (10): BSR20210486.
DOI: https://doi.org/10.1042/BSR20210486
Published: 04 October 2021
...Maoshu Zhu; Hui Zhang; Fuhua Lu; Zhaowei Wang; Yulong Wu; Huoshu Chen; Xin Fan; Zhijiang Yin; Fulong Liang Non-small cell lung cancer (NSCLC) is the most common subtype of lung cancer. Ubiquitination is closely related to the development of lung cancer. However, the biological importance of newly...
View article titled, USP52 inhibits cell proliferation by stabilizing PTEN protein in <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span>
Click here to open pdf in another window PDF for USP52 inhibits cell proliferation by stabilizing PTEN protein in <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span>
Articles

Retraction: Circular RNA hsa_circ_0072309 inhibits non-small cell lung cancer progression by sponging miR-580-3p

Journal: Bioscience Reports
Biosci Rep (2021) 41 (5): BSR-20194237_RET.
DOI: https://doi.org/10.1042/BSR-20194237_RET
Published: 04 May 2021
... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . hsa_circ_0072309 miR-580-3p non-small cell lung cancer This Retraction...
View article titled, Retraction: Circular RNA hsa_circ_0072309 inhibits <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span> progression by sponging miR-580-3p
Click here to open pdf in another window PDF for Retraction: Circular RNA hsa_circ_0072309 inhibits <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span> progression by sponging miR-580-3p
Articles

Association between microRNA-146a, -499a and -196a-2 SNPs and non-small cell lung cancer: a case–control study involving 2249 subjects

Hao Qiu, Zhiqiang Xie, Weifeng Tang, Chao Liu, Yafeng Wang, Haiyong Gu, Qingfeng Zheng
Journal: Bioscience Reports
Biosci Rep (2021) 41 (2): BSR20201158.
DOI: https://doi.org/10.1042/BSR20201158
Published: 17 February 2021
... and epithelial–mesenchymal transition. Thus, miRs may be implicated in the occurrence of non-small cell lung cancer (NSCLC). In the current investigation, we included 2249 subjects (1193 NSCLC patients and 1056 controls) and designed a study to identify the relationship of miR-146a rs2910164 C/G, -499a rs3746444...
View article titled, Association between microRNA-146a, -499a and -196a-2 SNPs and <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span>: a case–control study involving 2249 subjects
Click here to open pdf in another window PDF for Association between microRNA-146a, -499a and -196a-2 SNPs and <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span>: a case–control study involving 2249 subjects
Includes: Supplementary data
Articles

miR-371b-5p promotes cell proliferation, migration and invasion in non-small cell lung cancer via SCAI

Xue Luo, Xiaolei Zhang, Jianming Peng, Yan Chen, Wenhui Zhao, Xiuling Jiang, Landi Su, Mingqi Xie, Bo Lin
Journal: Bioscience Reports
Biosci Rep (2020) 40 (11): BSR20200163.
DOI: https://doi.org/10.1042/BSR20200163
Published: 13 November 2020
...Xue Luo; Xiaolei Zhang; Jianming Peng; Yan Chen; Wenhui Zhao; Xiuling Jiang; Landi Su; Mingqi Xie; Bo Lin Objective: Multiple gene targets have been reported for treatment of non-small cell lung cancer (NSCLC), however, the accompanying genetic tolerance was reported increasingly. Therefore...
View article titled, miR-371b-5p promotes cell proliferation, migration and invasion in <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span> via SCAI
Click here to open pdf in another window PDF for miR-371b-5p promotes cell proliferation, migration and invasion in <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span> via SCAI
Articles

LncRNA HAND2-AS1 inhibits proliferation and promotes apoptosis of non-small cell lung cancer cells by inactivating PI3K/Akt pathway

Ting Gao, Xiaoqiang Dai, Yindi Jiang, Xiaopeng He, Shuli Yuan, Peiwen Zhao
Journal: Bioscience Reports
Biosci Rep (2020) 40 (11): BSR20201870.
DOI: https://doi.org/10.1042/BSR20201870
Published: 02 November 2020
...Ting Gao; Xiaoqiang Dai; Yindi Jiang; Xiaopeng He; Shuli Yuan; Peiwen Zhao Background: Non-small cell lung cancer (NSCLC) is a major subtype of lung cancer and is correlated with high incidence and mortality rate. Functionality of lncRNA HAND2-AS1 is only reported in endometrioid endometrial...
View article titled, LncRNA HAND2-AS1 inhibits proliferation and promotes apoptosis of <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span> cells by inactivating PI3K&#x2F;Akt pathway
Click here to open pdf in another window PDF for LncRNA HAND2-AS1 inhibits proliferation and promotes apoptosis of <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span> cells by inactivating PI3K/Akt pathway
Articles

Clinicopathological and prognostic value of S100A4 expression in non-small cell lung cancer: a meta-analysis

Jing Zhang, Yanhui Gu, Xiaoli Liu, Ximin Rao, Guichuan Huang, Yao Ouyang
Journal: Bioscience Reports
Biosci Rep (2020) 40 (7): BSR20201710.
DOI: https://doi.org/10.1042/BSR20201710
Published: 30 July 2020
...). 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . meta analysis non-small cell lung cancer S100A4 Lung cancer is the most commonly occurring cancer...
View article titled, Clinicopathological and prognostic value of S100A4 expression in <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span>: a meta-analysis
Click here to open pdf in another window PDF for Clinicopathological and prognostic value of S100A4 expression in <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span>: a meta-analysis
Includes: Supplementary data
Articles

Correction: The roles of MASPIN expression and subcellular localization in non-small cell lung cancer

Journal: Bioscience Reports
Biosci Rep (2020) 40 (7): BSR-20200743_COR.
DOI: https://doi.org/10.1042/BSR-20200743_COR
Published: 30 June 2020
... The authors of the original article above article “The roles of MASPIN expression and subcellular localization in non-small cell lung cancer” (Bioscience Reports (2020) 40(5), DOI: 10.1042/BSR20200743) would like to correct Figure 6 B, as the IHC images of LUAD and LUSC were repeated due...
View article titled, Correction: The roles of MASPIN expression and subcellular localization in <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span>
Click here to open pdf in another window PDF for Correction: The roles of MASPIN expression and subcellular localization in <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span>
Articles

Expression of Concern: Circular RNA hsa_circ_0072309 inhibits non-small cell lung cancer progression by sponging miR-580-3p

Journal: Bioscience Reports
Biosci Rep (2020) 40 (6): BSR-20194237_EOC.
DOI: https://doi.org/10.1042/BSR-20194237_EOC
Published: 24 June 2020
... © 2020 The Author(s). 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . hsa_circ_0072309 non-small cell lung cancer miR-580-3p The Editorial...
View article titled, Expression of Concern: Circular RNA hsa_circ_0072309 inhibits <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span> progression by sponging miR-580-3p
Click here to open pdf in another window PDF for Expression of Concern: Circular RNA hsa_circ_0072309 inhibits <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span> progression by sponging miR-580-3p
Articles

The roles of MASPIN expression and subcellular localization in non-small cell lung cancer

Xiao-Fei Wang, Bo Liang, Da-Xiong Zeng, Wei Lei, Cheng Chen, Yan-Bin Chen, Jian-An Huang, Ning Gu, Ye-Han Zhu
Journal: Bioscience Reports
Biosci Rep (2020) 40 (5): BSR20200743.
DOI: https://doi.org/10.1042/BSR20200743
Published: 26 May 2020
...Xiao-Fei Wang; Bo Liang; Da-Xiong Zeng; Wei Lei; Cheng Chen; Yan-Bin Chen; Jian-An Huang; Ning Gu; Ye-Han Zhu Accumulating studies have confirmed that mammary serine protease inhibitor (MASPIN) plays an essential role in non-small cell lung cancer (NSCLC). However, results are still controversial...
View article titled, The roles of MASPIN expression and subcellular localization in <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span>
Click here to open pdf in another window PDF for The roles of MASPIN expression and subcellular localization in <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span>
Includes: Supplementary data
Articles

Circular RNA hsa_circ_0072309 inhibits non-small cell lung cancer progression by sponging miR-580-3p

Wenguang Pang, Fengliu Huang, Xin Zhang, Min Ye, Yanming Huang, Xiufang Huang, Jingzhuo Pang, Chengjie Cai, Zheng Wang
Journal: Bioscience Reports
Biosci Rep (2020) 40 (5): BSR20194237.
DOI: https://doi.org/10.1042/BSR20194237
Published: 04 May 2020
...Wenguang Pang; Fengliu Huang; Xin Zhang; Min Ye; Yanming Huang; Xiufang Huang; Jingzhuo Pang; Chengjie Cai; Zheng Wang Objective: Non-small cell lung cancer (NSCLC) continues to top the list of cancer mortalities worldwide. Early diagnosis and therapeutic interventions targeting NSCLC is becoming...
View article titled, Circular RNA hsa_circ_0072309 inhibits <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span> progression by sponging miR-580-3p
Click here to open pdf in another window PDF for Circular RNA hsa_circ_0072309 inhibits <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span> progression by sponging miR-580-3p
Articles

WITHDRAWN: MiR-760  inhibits the progression of non-small cell lung cancer through blocking ROS1 /Ras/Raf/MEK/ERK pathway

Wei Wang, Bin He
Journal: Bioscience Reports
Biosci Rep (2020) BSR20182483.
DOI: https://doi.org/10.1042/BSR20182483
Published: 29 April 2020
... The Author(s) 2020 This is an Accepted Manuscript; not the final Version of Record. You are encouraged to use the final Version of Record that, when published, will replace this manuscript and be freely available under a Creative Commons licence. Non-small cell lung cancer MiR-760 ROS1 Ras/Raf...
View article titled, WITHDRAWN: MiR-760  inhibits the progression of <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span> through blocking ROS1 &#x2F;Ras&#x2F;Raf&#x2F;MEK&#x2F;ERK pathway
Click here to open pdf in another window PDF for WITHDRAWN: MiR-760  inhibits the progression of <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span> through blocking ROS1 /Ras/Raf/MEK/ERK pathway
Articles

Knockdown of HSDL2 inhibits lung adenocarcinoma progression via down-regulating AKT2 expression

Yujia Shi, Zhengdao Mao, Yanhua Huang, Yun Sun, Qi Cao, Xiaowei Yin, Jianan Huang, Qian Zhang
Journal: Bioscience Reports
Biosci Rep (2020) 40 (4): BSR20200348.
DOI: https://doi.org/10.1042/BSR20200348
Published: 07 April 2020
... and distributed under the Creative Commons Attribution License 4.0 (CC BY) . gene chip hydroxysteroid dehydrogenase-like 2 lung adenocarcinoma non-small cell lung cancer prognosis Lung cancer has the highest mortality rate of all malignant tumors, and approximately 1.5 million people die from lung...
View article titled, Knockdown of HSDL2 inhibits lung adenocarcinoma progression via down-regulating AKT2 expression
Click here to open pdf in another window PDF for Knockdown of HSDL2 inhibits lung adenocarcinoma progression via down-regulating AKT2 expression
Articles

Preoperative systemic immune-inflammation index predicts prognosis and guides clinical treatment in patients with non-small cell lung cancer

Xue Yan, Guowei Li
Journal: Bioscience Reports
Biosci Rep (2020) 40 (3): BSR20200352.
DOI: https://doi.org/10.1042/BSR20200352
Published: 27 March 2020
...Xue Yan; Guowei Li Objectives: The purpose of the present study was to evaluate the prognostic value of a systemic immune-inflammation index (SII) and the relationship between SII and the effectiveness of postoperative treatment in patients with non-small cell lung cancer (NSCLC). Methods: A total...
View article titled, Preoperative systemic immune-inflammation index predicts prognosis and guides clinical treatment in patients with <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span>
Click here to open pdf in another window PDF for Preoperative systemic immune-inflammation index predicts prognosis and guides clinical treatment in patients with <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span>
Articles

LINC00461/miR-4478/E2F1 feedback loop promotes non-small cell lung cancer cell proliferation and migration

Qingxin Meng, Ming Liu, Ruyi Cheng
Journal: Bioscience Reports
Biosci Rep (2020) 40 (2): BSR20191345.
DOI: https://doi.org/10.1042/BSR20191345
Published: 25 February 2020
...Qingxin Meng; Ming Liu; Ruyi Cheng Non-small cell lung cancer (NSCLC) is a prevalent subtype of lung cancer, whose mortality is high. Long non-coding RNAs (lncRNAs) have caught rising attentions because of their intricate roles in regulating cancerization and cancer progression. Long intergenic non...
View article titled, LINC00461&#x2F;miR-4478&#x2F;E2F1 feedback loop promotes <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span> cell proliferation and migration
Click here to open pdf in another window PDF for LINC00461/miR-4478/E2F1 feedback loop promotes <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span> cell proliferation and migration
Includes: Supplementary data
Articles

Nicotine promotes the development of non-small cell lung cancer through activating LINC00460 and PI3K/Akt signaling

Hongying Zhao, Yu Wang, Xiubao Ren
Journal: Bioscience Reports
Biosci Rep (2019) 39 (6): BSR20182443.
DOI: https://doi.org/10.1042/BSR20182443
Published: 07 June 2019
... of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . apoptosis cell migration nicotine non-small cell lung cancer LINC00460 proliferation It is well known that mortality caused by lung cancer ranks first in cancer-related deaths worldwide [ 1...
View article titled, Nicotine promotes the development of <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span> through activating LINC00460 and PI3K&#x2F;Akt signaling
Click here to open pdf in another window PDF for Nicotine promotes the development of <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span> through activating LINC00460 and PI3K/Akt signaling
Articles

Up-regulated circular RNA VANGL1 contributes to progression of non-small cell lung cancer through inhibition of miR-195 and activation of Bcl-2

Liuxin Wang, Huiping Ma, Weixiang Kong, Bing Liu, Xueqing Zhang
Journal: Bioscience Reports
Biosci Rep (2019) 39 (6): BSR20182433.
DOI: https://doi.org/10.1042/BSR20182433
Published: 04 June 2019
... This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . apoptosis Bcl-2 circular RNA VANGL1 microRNA-195 non-small cell lung cancer Lung cancer is the most commonly...
View article titled, Up-regulated circular RNA VANGL1 contributes to progression of <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span> through inhibition of miR-195 and activation of Bcl-2
Click here to open pdf in another window PDF for Up-regulated circular RNA VANGL1 contributes to progression of <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span> through inhibition of miR-195 and activation of Bcl-2
Articles

Long noncoding RNA HOXA-AS2 promotes non-small cell lung cancer progression by regulating miR-520a-3p

Yunpeng Liu, Xingyu Lin, Shiyao Zhou, Peng Zhang, Guoguang Shao, Zhiguang Yang
Journal: Bioscience Reports
Biosci Rep (2019) 39 (5): BSR20190283.
DOI: https://doi.org/10.1042/BSR20190283
Published: 31 May 2019
... Attribution License 4.0 (CC BY) . HOXA-AS2 Long non-coding RNA miR-520a-3p non-small cell lung cancer proliferation Non-small cell lung cancer (NSCLC), accounting for approximately 80% of lung cancers, is one of the most malignant tumors worldwide with a low overall 5-year survival rate [ 1...
View article titled, Long noncoding RNA HOXA-AS2 promotes <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span> progression by regulating miR-520a-3p
Click here to open pdf in another window PDF for Long noncoding RNA HOXA-AS2 promotes <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span> progression by regulating miR-520a-3p
Articles

A novel bispecific c-MET/CTLA-4 antibody targetting lung cancer stem cell-like cells with therapeutic potential in human non-small-cell lung cancer

Jian-feng Li, Yuan-yuan Niu, Yan-li Xing, Feng Liu
Journal: Bioscience Reports
Biosci Rep (2019) 39 (5): BSR20171278.
DOI: https://doi.org/10.1042/BSR20171278
Published: 31 May 2019
...Jian-feng Li; Yuan-yuan Niu; Yan-li Xing; Feng Liu A novel paradigm in tumor biology suggests that non-small-cell lung cancer (NSCLC) growth is driven by lung cancer stem cell (LCSC) like cells, but t here are still not any effective strategies to remove LCSCs. The bispecific antibody (BsAb...
View article titled, A novel bispecific c-MET&#x2F;CTLA-4 antibody targetting lung cancer stem cell-like cells with therapeutic potential in human <span class="search-highlight">non</span>-<span class="search-highlight">small</span>-<span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span>
Click here to open pdf in another window PDF for A novel bispecific c-MET/CTLA-4 antibody targetting lung cancer stem cell-like cells with therapeutic potential in human <span class="search-highlight">non</span>-<span class="search-highlight">small</span>-<span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span>
Includes: Supplementary data
Articles

PDK-1 mediated Hippo–YAP–IRS2 signaling pathway and involved in the apoptosis of non-small cell lung cancer cells

Guofang Wang, Xiaomei Liu, Jiali Xie, Jinfei Meng, Xiaoqin Ni
Journal: Bioscience Reports
Biosci Rep (2019) 39 (5): BSR20182099.
DOI: https://doi.org/10.1042/BSR20182099
Published: 14 May 2019
..., the function and underlying mechanism of PDK-1 is remaining unclear. In the present study, our aim was to investigate the role and mechanisms of PDK-1 in human non-small cell lung cancer (NSCLC) cells. We first observed that PDK-1 was highly expressed in NSCLC cell lines. PDK-1 silence resulted...
View article titled, PDK-1 mediated Hippo–YAP–IRS2 signaling pathway and involved in the apoptosis of <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span> cells
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Articles

MiR-384 induces apoptosis and autophagy of non-small cell lung cancer cells through the negative regulation of Collagen α-1(X) chain gene

Qingkui Guo, Min Zheng, Ye Xu, Ning Wang, Wen Zhao
Journal: Bioscience Reports
Biosci Rep (2019) 39 (2): BSR20181523.
DOI: https://doi.org/10.1042/BSR20181523
Published: 01 February 2019
...Qingkui Guo; Min Zheng; Ye Xu; Ning Wang; Wen Zhao The present study aims to investigate the mechanism of miR-384 in non-small cell lung cancer (NSCLC) cell apoptosis and autophagy by regulating Collagen α-1(X) chain (COL10A1). Bioinformatics methods were applied to evaluate potential miRNAs...
View article titled, MiR-384 induces apoptosis and autophagy of <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span> cells through the negative regulation of Collagen α-1(X) chain gene
Click here to open pdf in another window PDF for MiR-384 induces apoptosis and autophagy of <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span> cells through the negative regulation of Collagen α-1(X) chain gene
Articles

Overexpression of miR-758 inhibited proliferation, migration, invasion, and promoted apoptosis of non-small cell lung cancer cells by negatively regulating HMGB

Guo-Hua Zhou, Yi-Yu Lu, Jing-Lian Xie, Zi-Kun Gao, Xiao-Bo Wu, Wei-Shen Yao, Wei-Guang Gu
Journal: Bioscience Reports
Biosci Rep (2019) 39 (1): BSR20180855.
DOI: https://doi.org/10.1042/BSR20180855
Published: 18 January 2019
...Guo-Hua Zhou; Yi-Yu Lu; Jing-Lian Xie; Zi-Kun Gao; Xiao-Bo Wu; Wei-Shen Yao; Wei-Guang Gu Non-small cell lung cancer (NSCLC) is one of the most fatal types of cancer with significant mortality and morbidity worldwide. MicroRNAs (miRs) have been confirmed to have positive functions in NSCLC...
View article titled, Overexpression of miR-758 inhibited proliferation, migration, invasion, and promoted apoptosis of <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span> cells by negatively regulating HMGB
Click here to open pdf in another window PDF for Overexpression of miR-758 inhibited proliferation, migration, invasion, and promoted apoptosis of <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span> cells by negatively regulating HMGB
Includes: Supplementary data
Articles

LncRNA HAND2-AS1 inhibits non-small cell lung cancer migration, invasion and maintains cell stemness through the interactions with TGF-β1

Feng Miao, Ji Chen, Meng Shi, Yang Song, Zhiming Chen, Liewen Pang
Journal: Bioscience Reports
Biosci Rep (2019) 39 (1): BSR20181525.
DOI: https://doi.org/10.1042/BSR20181525
Published: 11 January 2019
...Feng Miao; Ji Chen; Meng Shi; Yang Song; Zhiming Chen; Liewen Pang LncRNA HAND2-AS1 is characterized as a tumor suppressor involved in several types of malignancies, but its role in non-small cell lung cancer (NSCLC) is unknown. Our study was carried out to investigate the involvement of lncRNA...
View article titled, LncRNA HAND2-AS1 inhibits <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span> migration, invasion and maintains cell stemness through the interactions with TGF-β1
Click here to open pdf in another window PDF for LncRNA HAND2-AS1 inhibits <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span> migration, invasion and maintains cell stemness through the interactions with TGF-β1
Articles

Long non-coding RNA SNHG14 exerts oncogenic functions in non-small cell lung cancer through acting as an miR-340 sponge

Zhenhua Zhang, Yong Wang, Wei Zhang, Junyan Li, Weiliang Liu, Wenming Lu
Journal: Bioscience Reports
Biosci Rep (2019) 39 (1): BSR20180941.
DOI: https://doi.org/10.1042/BSR20180941
Published: 03 January 2019
...Zhenhua Zhang; Yong Wang; Wei Zhang; Junyan Li; Weiliang Liu; Wenming Lu Long non-coding RNA (lncRNA) SNHG14 is previously found to be overexpressed in several types of cancers. However, the clinical significance and biological function of SNHG14 in non-small cell lung cancer (NSCLC) are still...
View article titled, Long non-coding RNA SNHG14 exerts oncogenic functions in <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span> through acting as an miR-340 sponge
Click here to open pdf in another window PDF for Long non-coding RNA SNHG14 exerts oncogenic functions in <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span> through acting as an miR-340 sponge
Articles

lncRNA Gm15290 promotes cell proliferation and invasion in lung cancer through directly interacting with and suppressing the tumor suppressor miR-615-5p

Yu Dong, Xiaoying Huo, Ruiying Sun, Zhiyan Liu, Miaoyi Huang, Shuanying Yang
Journal: Bioscience Reports
Biosci Rep (2018) 38 (5): BSR20181150.
DOI: https://doi.org/10.1042/BSR20181150
Published: 31 October 2018
... cancer has become the leading cause of cancer death in China. Non-small cell lung cancers (NSCLC), including squamous cell carcinoma, adenocarcinoma, and large cell carcinoma, account for more than 80% of lung cancer cases [ 1 ]. In contrast with small cell lung cancer cells, the growth and division...
View article titled, lncRNA Gm15290 promotes cell proliferation and invasion in lung cancer through directly interacting with and suppressing the tumor suppressor miR-615-5p
Click here to open pdf in another window PDF for lncRNA Gm15290 promotes cell proliferation and invasion in lung cancer through directly interacting with and suppressing the tumor suppressor miR-615-5p
Articles

Overexpressed C14orf166 associates with disease progression and poor prognosis in non-small-cell lung cancer

Yan-Wu Zhou, Rong Li, Chao-Jun Duan, Yang Gao, Yuan-Da Cheng, Chun-Fang Zhang
Journal: Bioscience Reports
Biosci Rep (2018) 38 (5): BSR20180479.
DOI: https://doi.org/10.1042/BSR20180479
Published: 14 September 2018
... of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . C14orf166 Clinicopathology Disease progression Non-small cell lung cancer Prognosis Lung cancer is a well-known malignant disease, with the highest morbidity and mortality worldwide, moreover...
View article titled, Overexpressed C14orf166 associates with disease progression and poor prognosis in <span class="search-highlight">non</span>-<span class="search-highlight">small</span>-<span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span>
Click here to open pdf in another window PDF for Overexpressed C14orf166 associates with disease progression and poor prognosis in <span class="search-highlight">non</span>-<span class="search-highlight">small</span>-<span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span>
Articles

A regulatory circuitry comprising TP53, miR-29 family, and SETDB1 in non-small cell lung cancer

Bifeng Chen, Jingdong Wang, Jieling Wang, Huan Wang, Xiuli Gu, Liang Tang, Xianhong Feng
Journal: Bioscience Reports
Biosci Rep (2018) 38 (5): BSR20180678.
DOI: https://doi.org/10.1042/BSR20180678
Published: 14 September 2018
...Bifeng Chen; Jingdong Wang; Jieling Wang; Huan Wang; Xiuli Gu; Liang Tang; Xianhong Feng Lung cancer is a malignant tumor with high fatality rate and causes great harm to human economic life. Non-small cell lung cancer (NSCLC) is the most common type of lung cancer. With the rapid development...
View article titled, A regulatory circuitry comprising TP53, miR-29 family, and SETDB1 in <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span>
Click here to open pdf in another window PDF for A regulatory circuitry comprising TP53, miR-29 family, and SETDB1 in <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span>
Articles

Wnt5a promotes epithelial-to-mesenchymal transition and metastasis in non-small-cell lung cancer

Biao Wang, Zhen Tang, Huiyuan Gong, Li Zhu, Xuegang Liu
Journal: Bioscience Reports
Biosci Rep (2017) 37 (6): BSR20171092.
DOI: https://doi.org/10.1042/BSR20171092
Published: 29 November 2017
...Biao Wang; Zhen Tang; Huiyuan Gong; Li Zhu; Xuegang Liu A recent study indicated that high Wnt5a expression is associated with poor prognosis in non-small-cell lung cancer (NSCLC) patients; however, the underlying mechanism was not clear yet. Immunohistochemistry and Western blotting were performed...
View article titled, Wnt5a promotes epithelial-to-mesenchymal transition and metastasis in <span class="search-highlight">non</span>-<span class="search-highlight">small</span>-<span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span>
Click here to open pdf in another window PDF for Wnt5a promotes epithelial-to-mesenchymal transition and metastasis in <span class="search-highlight">non</span>-<span class="search-highlight">small</span>-<span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span>
Articles

Sensitivity of non-small cell lung cancer to erlotinib is regulated by the Notch/miR-223/ FBXW7 pathway

Haiwei Zhang, Fanglin Chen, Yongpeng He, Lin Yi, Chuang Ge, Xiaolong Shi, Chao Tang, Donglin Wang, Yongzhong Wu, Weiqi Nian
Journal: Bioscience Reports
Biosci Rep (2017) 37 (3): BSR20160478.
DOI: https://doi.org/10.1042/BSR20160478
Published: 21 June 2017
... to the effects of epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) used in treatment of non-small cell lung cancer (NSCLC) remains to be elucidated. The levels of miR-223 in parental cell line (HCC827) and erlotinib resistant HCC827 cell line (HCC827/ER) were detected by qRT-PCR. HCC827/ER...
View article titled, Sensitivity of <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span> to erlotinib is regulated by the Notch&#x2F;miR-223&#x2F; FBXW7 pathway
Click here to open pdf in another window PDF for Sensitivity of <span class="search-highlight">non</span>-<span class="search-highlight">small</span> <span class="search-highlight">cell</span> <span class="search-highlight">lung</span> <span class="search-highlight">cancer</span> to erlotinib is regulated by the Notch/miR-223/ FBXW7 pathway
Includes: Supplementary data