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Keywords: NLRP3
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Biosci Rep (2020) 40 (8): BSR20200689.
Published: 07 August 2020
...-inflammatory diseases, NOD-like receptors such as NLRP3 have been identified as a central component to immune-mediated pathology. However, to date the role of NLRP3 in biliary diseases has been poorly explored. Here, we addressed the role of NLRP3 in the OVAbil mouse model of antigen-mediated cholangitis...
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Biosci Rep (2019) 39 (8): BSR20190419.
Published: 23 August 2019
... prevented H 2 O 2 -induced death and degeneration of chondrocytes partly by enhancing antioxidant capacity. Mechanistically, Dex attenuated H 2 O 2 -mediated activation of NF-κB and NACHT, LRR, and PYD domains-containing protein 3 (NLRP3), both of which play key roles in inflammation and inflammatory damage...
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Biosci Rep (2019) 39 (1): BSR20181117.
Published: 08 January 2019
... and pyrin domain containing 3 (NLRP3) partly accounts for the activation of pro-inflammatory factors. The aim of the present study was to investigate whether NLRP3 was involved in the protective effect of estrogen against allergic airway inflammation. Methods: An ovariectomy was performed on female C57BL/6...
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Biosci Rep (2018) 38 (3): BSR20180282.
Published: 22 May 2018
... in pterygium pathogenesis. The expression of nod-like receptor pyrins-3 (NLRP3), caspase-1, IL-18, and IL-1β was analyzed in 60 human pterygium tissues and 60 human conjunctival epithelium tissues using real-time quantitative polymerase chain reaction (qRT-PCR) and Western blot analysis. Human conjunctival...
Includes: Supplementary data