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Keywords: NF-kB
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Biosci Rep (2022) 42 (5): BSR20212418.
Published: 13 May 2022
... License 4.0 (CC BY) . Colitis-associated cancer Colorectal cancer Interleukin-6 Lipocalin 2 NF-kB STAT3 Inflammatory bowel diseases (IBDs) can be divided into two major disorders: ulcerative colitis and Crohn’s disease [ 1 ]. Although colitis-associated colorectal cancer (CAC) accounts...
Biosci Rep (2022) 42 (1): BSR20212062.
Published: 18 January 2022
... BY) . hypoxic HUVECs IL-1β miR-24-3p NF-kB NKAP Acute myocardial infarction (AMI) and heart failure (HF) are often the leading causes of death and disability worldwide, especially in developed countries [ 1–3 ]. AMI is an event of myocardial necrosis that may lead to functional loss in the diastolic...
Biosci Rep (2021) 41 (5): BSR20204203.
Published: 27 May 2021
... demonstrated the synergistic effects of orlistat combined with enzalutamide in vitro and castration in viv o on human PCa. castration therapy enzalutamide fatty acid synthase NF-kB orlistat prostate cancer Prostate cancer (PCa) is the second most frequent cancer and the fifth leading cause...
Includes: Supplementary data
Biosci Rep (2019) 39 (9): BSR20192466.
Published: 24 September 2019
..., glypican 3 (GPC3), nuclear factor κ-light-chain-enhancer of activated B cells (NF-kB), epidermal growth factor receptor, ERK1/2, tumor necrosis factor-α (TNF-α), regenerating islet-derived 1 and 3 α (REG1A and 3A), substance P (SP)/neurokinin-1 receptor and PARP-1. The present review describes the key role...
Biosci Rep (2019) 39 (4): BSR20181709.
Published: 09 April 2019
... the Creative Commons Attribution License 4.0 (CC BY) . cancer inflammasome NLR NOD1 NOD2 NF-kB The innate immune system is our first line of defense against infections from an enormous diversity of microbes and viruses. The human innate immunity relies on a wide range of receptors...
Biosci Rep (2019) 39 (3): BSR20182221.
Published: 01 March 2019
..., NF-kB, and p38 signaling pathway were determined, and found that overexpression of PAK1 activated NF-kB and p38. Inhibition of PAK1 by shRNA or small molecule inhibitor FRAX597 decreased NF-kB and p38 activity, and alleviated the pathological damage in the pancreas, including decreasing the amylase...