... License 4.0 (CC BY) . Colitis-associated cancer Colorectal cancer Interleukin-6 Lipocalin 2 NF-kB STAT3 Inflammatory bowel diseases (IBDs) can be divided into two major disorders: ulcerative colitis and Crohn’s disease [ 1 ]. Although colitis-associated colorectal cancer (CAC) accounts...

... BY) . hypoxic HUVECs IL-1β miR-24-3p NF-kB NKAP Acute myocardial infarction (AMI) and heart failure (HF) are often the leading causes of death and disability worldwide, especially in developed countries [ 1–3 ]. AMI is an event of myocardial necrosis that may lead to functional loss in the diastolic...

... and escaping apoptosis [ 9 ]. Signals from activated receptor tyrosine kinases (RTKs), Ras-Raf-MEK-ERK1/2 and PI3K/AKT machineries in turn can activate several transcription factors, such as NF-kB and its downstream effector proteins including MMP-9, cyclooxygenase-2, cyclin D1, EMT, VEGF and Bcl-2...

..., glypican 3 (GPC3), nuclear factor κ-light-chain-enhancer of activated B cells (NF-kB), epidermal growth factor receptor, ERK1/2, tumor necrosis factor-α (TNF-α), regenerating islet-derived 1 and 3 α (REG1A and 3A), substance P (SP)/neurokinin-1 receptor and PARP-1. The present review describes the key role...

... published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . cancer inflammasome NLR NOD1 NOD2 NF-kB In humans, innate immune receptors are classified into several families [ 3 ]. Amongst the most well...

... This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Acute pancreatitis FRAX597 Inflammation NF-kB PAK1 p38 Acute pancreatitis (AP) is a relatively common...