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Keywords: NF-κB
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Biosci Rep (2023) 43 (2): BSR20221927.
Published: 27 February 2023
... and in silico screening revealed that ambroxol may impede cell entry of SARS-CoV-2 by binding to neuropilin-1. Ambroxol could also interact with multiple inflammatory factors and signaling pathways, especially nuclear factor kappa B (NF-κB), to interfere cytokines cascade activated by SARS-CoV-2 internalization...
Includes: Supplementary data
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Biosci Rep (2022) 42 (7): BSR-2019-1611_RET.
Published: 27 July 2022
... © 2022 The Author(s). 2022 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . AKT3 breast cancer metastasis miRNA NF-κB This article is being...
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Biosci Rep (2022) 42 (1): BSR20212196.
Published: 24 January 2022
... in the acute toxicity study of Pun. Conclusion: Pun improves LPS-induced ALI mainly through its anti-inflammatory properties, which is associated with nuclear factor-κB (NF-κB) and MAPKs signaling pathways. The study implied that Pun maybe a potent agent against ALI in future clinic. Correspondence...
Includes: Supplementary data
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Biosci Rep (2019) 39 (8): BSR20190419.
Published: 23 August 2019
... prevented H 2 O 2 -induced death and degeneration of chondrocytes partly by enhancing antioxidant capacity. Mechanistically, Dex attenuated H 2 O 2 -mediated activation of NF-κB and NACHT, LRR, and PYD domains-containing protein 3 (NLRP3), both of which play key roles in inflammation and inflammatory damage...
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Biosci Rep (2019) 39 (8): BSR20191611.
Published: 23 August 2019
...-5p. Furthermore, decreased miR-16-5p in cell and animal models enhanced migration and proliferation of breast cancer cells, stimulated cell cycle and reduced cell apoptosis. Finally, we found miR-16-5p restrained the NF-κB pathway and decreased AKT3 gene, thereby suppressing the breast cancer...
Includes: Supplementary data
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Biosci Rep (2019) 39 (7): BSR20181613.
Published: 05 July 2019
..., overexpression of PLCE1 increased the phosphorylation of p38, ERK1/2, and nuclear factor-κ B (NF-κB) P65 while knockdown of PLCE1 inhibited their phosphorylation. In conclusion, the present study provided evidence that PLCE1 was up-regulated in H/R H9c2 cell and I/R rat. Overexpression of PLCE1 promoted...
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Biosci Rep (2018) 38 (4): BSR20180540.
Published: 31 July 2018
... the expression of p-IkBα and CD69, and CD25in T cells. MiR-128-3p targets TNFAIP3 to regulate its expression. MiR-128-3p knockdown significantly suppressed the activity of nuclear factor κB (NF-κB) and T cells by up-regulating TNFAIP3, while cells co-transfected with si-TNFAIP3 abolished the effects of MiR-128...
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Biosci Rep (2014) 34 (4): e00127.
Published: 29 July 2014
... homoeostasis and cellular survival. In mammalian cells, hypoxia not only activates the HIF (hypoxia-inducible factor) family, but also additional transcription factors such as NF-κB (nuclear factor κB). Here we show that hypoxia activates the IKK–NF-κB [IκB (inhibitor of nuclear factor κB)–NF-κB] pathway...
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