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Keywords: Mortaparib
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Articles
Biosci Rep (2021) 41 (10): BSR20212156.
Published: 14 October 2021
...-regulate their expression. Here, we report experimental and computational analyses of two small molecules, Mortaparib and Mortaparib Plus that were initially identified as dual novel inhibitors of mortalin and PARP-1, for their activity against SARS-CoV-2. In silico analyses showed that Mortaparib Plus...
Includes: Supplementary data
Articles
Biosci Rep (2021) BSR20212156.
Published: 04 October 2021
... small molecules, Mortaparib and Mortaparib Plus that were initially identified as dual novel inhibitors of mortalin and PARP-1, for their activity against SARS-CoV-2. In silico analyses showed that Mortaparib Plus , but not Mortaparib, stably binds into the catalytic pocket of TMPRSS2. In vitro analysis...