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Keywords: MAPKs
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Articles

Sec-O-glucosylhamaudol suppressed inflammatory reaction induced by LPS in RAW264.7 cells through inhibition of NF-κB and MAPKs signaling

Guiming Liu, Jing Xie, Yurui Shi, Rongda Chen, Li Li, Mengxue Wang, Meizhu Zheng, Jiaming Xu
Journal: Bioscience Reports
Biosci Rep (2020) 40 (2): BSR20194230.
DOI: https://doi.org/10.1042/BSR20194230
Published: 14 February 2020
... and TNF-α in Raw264.7 murine macrophages stimulated by LPS. Real-time PCR assay demonstrated the SOG dose-dependently inhibited transcription of these cytokines as well. In addition, it was also found that NF-κB activation and MAPKs phosphorylation including p38, JNK and ERK1/2 induced by LPS were...
View article titled, Sec-O-glucosylhamaudol suppressed inflammatory reaction induced by LPS in RAW264.7 cells through inhibition of NF-κB and <span class="search-highlight">MAPKs</span> signaling
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Articles

CFTR protects against vascular inflammation and atherogenesis in apolipoprotein E-deficient mice

Zhengzhang Li, Zhe Shen, Haoping Xue, Shi Cheng, Qun Ji, Yutan Liu, Xiangjun Yang
Journal: Bioscience Reports
Biosci Rep (2017) 37 (4): BSR20170680.
DOI: https://doi.org/10.1042/BSR20170680
Published: 07 July 2017
.... Moreover, in vitro experiments showed that overexpression of CFTR inhibited ox-LDL-induced the migration of peritoneal macrophages. Finally, it was observed that CFTR up-regulation suppressed NFκB and MAPKs activity induced by ox-LDL. Inhibition of JNK or ERK abrogated CFTR down-regulation induced NFκB...
View article titled, CFTR protects against vascular inflammation and atherogenesis in apolipoprotein E-deficient mice
Click here to open pdf in another window PDF for CFTR protects against vascular inflammation and atherogenesis in apolipoprotein E-deficient mice
Includes: Supplementary data