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Biosci Rep (2022) 42 (1): BSR20212196.
Published: 24 January 2022
... and regulated the biomarkers in BALF. Furthermore, Pun dose-dependently reduced the phosphor protein levels of p65, IκBα, ERK1/2, JNK and p38 in lung tissue, which exhibited that the effect of Pun related to mitogen-activated protein kinases (MAPKs) pathway. More importantly, there was no toxicity was observed...
Includes: Supplementary data
Nanwen Zhang, Zhiwei Liu, Hongbin Luo, Weifang Wu, Kaimei Nie, Lin Cai, Shuangyu Tan, Xiaole Chen, Ying Huang, Jiaxing Liu, Meina Lv, Xin Zhang, Yun Fan, Yuying Lin, Shennan Ye, Yang Liu, Lixian Wu, Jianhua Xu
Biosci Rep (2019) 39 (9): BSR20182263.
Published: 03 September 2019
... protein kinase (MAPK) pathway by Western blot analysis. The enzyme-linked immunosorbent assay (ELISA) was employed to measure synovial fluid levels of tumor necrosis factor-α (TNF-α), interleukin (IL)-6, IL-1β and IL-10. Results: Compared with AIA group, FM0807 reduced the AI and swelling of the injected...
Camilo Gomez, Laisel Martinez, Annia Mesa, Juan C. Duque, Luis A. Escobar, Si M. Pham, Roberto I. Vazquez-Padron
Biosci Rep (2015) 35 (4): e00227.
Published: 14 July 2015
.... Early apoptotic VSMC were rich in p38 mitogen-activated protein kinase (MAPK) and the transcription factor c-Jun and secreted IL-6 and GRO/KC into the milieu as determined using multiplex bead assays. Neointima thickness increased steadily starting on day 3 as a result of pronounced repopulation...
John C. Salerno, Dipak K. Ghosh, Raj Razdan, Katy A. Helms, Christopher C. Brown, Jonathan L. McMurry, Emily A. Rye, Carol A. Chrestensen
Biosci Rep (2014) 34 (5): e00137.
Published: 17 September 2014
...John C. Salerno; Dipak K. Ghosh; Raj Razdan; Katy A. Helms; Christopher C. Brown; Jonathan L. McMurry; Emily A. Rye; Carol A. Chrestensen eNOS (endothelial nitric oxide synthase) contains a MAPK (mitogen-activated protein kinase)-binding site associated with a major eNOS control element. Purified...
Biosci Rep (2014) 34 (1): e00089.
Published: 14 January 2014
... and paracrine acting growth factors involved in molecular processes of tumour – stroma interaction, transforming growth factor-beta1 (TGFβ1), a 25kDa homodimeric protein, plays a pivotal role [ 2 , 3 , 9 , 10 ]. MAPK myofibroblast NAD(P)H oxidase reactive oxygen species TGFβ1 tumour–stroma interaction...