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Keywords: EGFR
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Biosci Rep (2020) 40 (5): BSR20191188.
Published: 05 May 2020
...) involving specific genes could modulate the risk of LSCC related to known carcinogens by modifying cellular responses, but not all genetic associations are known. In a case–control study, we assess the associations between cyclooxygenase-2 (COX2), epidermal growth factor (EGF), EGF receptor (EGFR...
Includes: Supplementary data
Biosci Rep (2020) 40 (2): BSR20194335.
Published: 28 February 2020
... metalloproteinase (MMP)-2, -7, and -9, which activate PI3K–AKT. SKA3 was also found to bind and activate EGFR to activate PI3K–AKT. In summary, we identify a role for SKA3 in LUAD metastasis through its ability to bind EFGR and activate PI3K–AKT signaling. Trizol was added to cell/tissues for RNA extraction...
Biosci Rep (2020) 40 (2): BSR20193524.
Published: 07 February 2020
... of oxycodone in cancer cells. Materials and Methods: Proliferation, survival and migration assays were performed on multiple types of cancer cells. Epithelial growth factor receptor (EGFR)/ERK/Akt pathway and oxidative stress were investigated after oxycodone treatment. Results: Oxycodone can either stimulate...
Biosci Rep (2019) 39 (1): BSR20181556.
Published: 08 January 2019
... expression levels of miR-1296-5p were associated with advanced clinical stage. Moreover, miR-1296-5p inhibited cell proliferation, migration, and invasion in SGC-7901 and MGC-803 cells. Then, we identified CDK6 and EGFR as novel targets of miR-1296-5p by a luciferase activity assay. Furthermore...