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Keywords: DNA integration
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Biosci Rep (2021) 41 (1): BSR20203595.
Published: 05 January 2021
... then used this to investigate targeting of the casposase-catalysed DNA integration reactions to specific DNA sites that would allow insertion of defined DNA payloads. Casposase–Cas9 fusions were engineered that were catalytically proficient in vitro and generated RNA-guided DNA integration products from...
Includes: Supplementary data