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Keywords: Cell proliferation
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Biosci Rep (2023) 43 (5): BSR20230028.
Published: 05 May 2023
..., immune checkpoint genes (ICPGs), copy number alterations (CNA), and tumor mutation burden (TMB) were also closely associated with PPP1R81 expression in LGG. In vitro experiments demonstrated that PPP1R81 was up-regulated and closely interrelated with cell proliferation and cell cycle in LGG. Conclusion...
Includes: Supplementary data
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Biosci Rep (2023) 43 (2): BSR-2017-1150_EOC.
Published: 09 February 2023
... © 2023 The Author(s). 2023 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . apoptosis cell proliferation growth arrest-specific 5 inflammasome long...
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Biosci Rep (2021) 41 (6): BSR20210093.
Published: 10 June 2021
... mechanism. Methods: After treatment with erianin, MTT assay was employed to determine the MDA-MB-231 and EFM-192A cell proliferation, the nucleus morphological changes were observed by DAPI staining. The cell cycle and apoptotic proportion were detected by flow cytometry. Western blot was performed...
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Biosci Rep (2021) 41 (4): BSR-20191221_RET.
Published: 14 April 2021
... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Cervical cancer cell invasion cell migration cell proliferation CDK5 miR...
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Biosci Rep (2020) 40 (12): BSR20200936.
Published: 14 December 2020
... cell proliferation and inhibit apoptosis. Correspondence: Shengjun Luo ( luosheng0618@foxmail.com ) * These authors contributed equally to this work. 30 03 2020 30 09 2020 16 11 2020 27 11 2020 © 2020 The Author(s). 2020 This is an open access article...
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Biosci Rep (2020) 40 (7): BSR-20192104_RET.
Published: 09 July 2020
... © 2020 The Author(s). 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Cell adhesion Cell migration Cell proliferation Chemotaxis Hematopoietic...
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Biosci Rep (2020) 40 (7): BSR-20191221_EOC.
Published: 02 July 2020
... © 2020 The Author(s). 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Cervical cancer cell invasion cell migration cell proliferation CDK5 miR...
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Biosci Rep (2020) 40 (7): BSR-20192104_EOC.
Published: 02 July 2020
... © 2020 The Author(s). 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Cell adhesion Cell migration Cell proliferation Chemotaxis Hematopoietic...
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Biosci Rep (2020) 40 (6): BSR20193815.
Published: 15 June 2020
... of SNPRA1 inhibited the cell proliferation, colony formation and xenografted tumorigenesis of HCC cells. Apoptosis was induced by SNPRA1 down-regulation. Mechanistically, SNPRA1 was stimulated by mTOR activation. In addition, whole-genome microarray analysis identified that 262 genes were up-regulated...
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Biosci Rep (2020) 40 (6): BSR20193788.
Published: 03 June 2020
...Li-Juan Ma; Jun Wu; En Zhou; Juan Yin; Xu-Ping Xiao MiRNAlet-7a is associated with the tumorigenesis of laryngeal squamous cell carcinoma (LSCC). Our study was designed to infer whether let-7a targets high-mobility AT-hook 2 (HMGA2) and suppresses laryngeal carcinoma cell proliferation, invasion...
Includes: Supplementary data
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Biosci Rep (2020) 40 (3): BSR20192104.
Published: 20 March 2020
... the Creative Commons Attribution License 4.0 (CC BY) . Cell adhesion Cell migration Cell proliferation Chemotaxis Hematopoietic stem cells Microvascular endothelial cells Hematopoietic stem cell (HSC) is a type of adult stem cells, whose self-renewal, maintenance, apoptosis and motional...
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Biosci Rep (2019) 39 (7): BSR20191221.
Published: 26 July 2019
...Elena Kapora; Shujun Feng; Wei Liu; Indira Sakhautdinova; Bo Gao; Wenhua Tan MicroRNAs (miRs) are considered to be tumor suppressors or oncogenes as they regulate cell proliferation, migration, invasion, and differentiation. Recently, microRNA-505 (miR-505) has been reported as being involved...
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Biosci Rep (2019) 39 (7): BSR20181788.
Published: 26 July 2019
.... In the present study, we focussed on a significantly down-regulated miRNA, miR-144-3p, and investigated its role in high glucose (HG) induced cell proliferation. Our data showed that miR-144-3p mimics significantly inhibited HG induced cell proliferation and reduced the percentage of cells in S phase. HG induced...
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Biosci Rep (2019) 39 (4): BSR20190040.
Published: 05 April 2019
... and participants. The present study was approved by the Ethics Committee of The First Hospital of Lanzhou University. The present study was conducted in accordance with the Declaration of Helsinki and written informed consent was obtained from the participant. Apoptosis Cell proliferation Cell cycle...
Includes: Supplementary data
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Biosci Rep (2019) 39 (4): BSR20182186.
Published: 02 April 2019
... that in adjacent tissues and closely correlated with histological grade and lymph node (LN) status. Patients with high SNHG20 showed a shorter overall survival (OS) and SNHG20 was an independent risk factor for the prognosis of serous EOC. Knockdown of SNHG20 remarkably inhibited EOC cell proliferation, migration...
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Biosci Rep (2019) 39 (1): BSR20181290.
Published: 08 January 2019
... different regulations on the cell proliferation. It has been demonstrated that TIMP-1 plays an important role in the osteogenesis of osteoblasts and MSCs [ 18–20 ]. Grässel et al. [ 21 ] report that during osteochondrogenic differentiation of rat adult mesenchymal progenitor cells, TIMP-1 is highly...
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Biosci Rep (2018) 38 (5): BSR20181042.
Published: 28 September 2018
... and distributed under the Creative Commons Attribution License 4.0 (CC BY) . apoptosis cell proliferation diabetes endothelial cells HDAC2 MnSOD Diabetes is a serious and increasing global health burden, and estimates of prevalence are essential for appropriate allocation of resources...
Includes: Supplementary data
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Biosci Rep (2018) 38 (5): BSR20180538.
Published: 19 September 2018
... 04 2018 13 07 2018 30 07 2018 30 07 2018 © 2018 The Author(s). 2018 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . cell proliferation...
Includes: Supplementary data
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Biosci Rep (2018) 38 (4): BSR20171675.
Published: 13 July 2018
... elevated in tumor tissues and negatively correlated with miR-1284 expression. MiR-1284 exerted its function by directly binding to 3′-UTR of HMGB1 and regulates expression of HMGB1. The overexpression of miR-1284 inhibited the cell proliferation and migration, and altered the protein expression...
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Biosci Rep (2018) 38 (2): BSR20171150.
Published: 16 March 2018
... the cellular mechanism and clinical value of lncRNA GAS5 in ovarian cancer. Methods: Quantitative real-time PCR was used to detect mRNA level of lncRNA GAS5 in 20 ovarian cancer tissues. The effect of lncRNA GAS5 on cell proliferation was performed using CCK-8 assay. Cell apoptosis was evaluated by flow...
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Biosci Rep (2017) 37 (6): BSR20171038.
Published: 12 December 2017
... specimens and cell lines. Moreover, the inhibition of miR-6743-5p caused a significant inhibition of cell proliferation and a marked promotion of cell apoptosis in glioma cells, and this phenotype was rescued by GRIM-19 knockdown. Finally, the inhibition of miR-6743-5p expression suppressed...
Includes: Supplementary data
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Biosci Rep (2017) 37 (6): BSR20171039.
Published: 21 November 2017
... that is dysregulated to promote malignant cell behaviour. Loss of POPDC1 expression has been correlated with enhanced cancer cell proliferation, migration, invasion, metastasis, drug resistance and poor patient survival in various human cancers [ 9 – 13 ]. Suppression of POPDC1 has further been shown to promote cell...
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Biosci Rep (2017) 37 (5): BSR20171019.
Published: 17 October 2017
... lines. Linc00460 expression was positively correlated with ESCC TNM stage, lymph node metastasis, and predicted poor prognosis. In vitro experiments showed that linc00460 depletion suppressed ESCC cell growth through regulating cell proliferation and cell cycle; in additional, linc00460 depletion...
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Biosci Rep (2016) 36 (6): e00424.
Published: 09 December 2016
... functional role in breast cancer has not been well characterized. In the present study, SIN1 is associated with the progression and survival of breast cancer patients, as well as human breast cancer cell proliferation and migration. SIN1 mRNA level was significantly up-regulated in human breast cancer...
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Biosci Rep (2015) 35 (5): e00245.
Published: 10 September 2015
... and distributed under the Creative Commons Attribution License 3.0. cell proliferation differentiation microRNA neural stem cells 9 4 2015 16 6 2015 22 6 2015 21 7 2015 In the present study, miR-146 promoted spontaneous differentiation of neural stem cells (NSCs...