1-50 of 51
Keywords: Bioinformatics
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Articles
Biosci Rep (2023) 43 (5): BSR20230067.
Published: 18 May 2023
... . In addition, quantitative proteomics and bioinformatics analysis confirmed that PPT1 acts by affecting the metabolism, localization, and function of various macromolecular proteins. The present study reveals that PPT1 could be a promising therapeutic target for the treatment of HCC. These findings provided...
Includes: Supplementary data
Articles
Articles
Biosci Rep (2022) 42 (8): BSR20212835.
Published: 31 August 2022
... investigated by bioinformatic analyses. Results: A ferroptosis-related gene signature ( ALOX5, TFRC, PHKG2, FADS2, NOX1 ) was constructed using multivariate Cox regression analysis and represented as a risk score. Overall survival (OS) probability was significantly lower in the high-risk group than in the low...
Articles
Biosci Rep (2022) 42 (7): BSR20220251.
Published: 15 July 2022
... Attribution License 4.0 (CC BY) . acetylation/deacetylation acetyltransferases bioinformatics immunomodulation inflammation toll-like receptors Inflammation is central to many diseases such as cancer, asthma, sepsis, and cardiovascular diseases [ 1 ] and is caused by infection from various...
Includes: Supplementary data
Articles
Biosci Rep (2022) 42 (1): BSR20211939.
Published: 28 January 2022
... (CC BY) . bioinformatics CCNB2 diagnosis and prognosis biomarkers immune infiltrates Low-grade glioma Low-grade glioma (LGG) is a common primary malignant tumor, which accounts for ∼20% of primary brain tumors [ 1 ]. Clinically, surgical resection, chemotherapy, radiotherapy...
Articles
Biosci Rep (2021) 41 (12): BSR20212403.
Published: 22 December 2021
..., the mechanisms of CXCL3 in head and neck squamous cell carcinoma (HNSCC) remain unclear. In our study, multiple databases were used to explore the expression level, prognostic value, and related mechanisms of CXCL3 in human HNSCC through bioinformatic methods. We also performed further experiments in vivo...
Includes: Supplementary data
Articles
Articles
Biosci Rep (2021) 41 (12): BSR20212026.
Published: 08 December 2021
... and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Bioinformatics OV Platinum resistance Prognosis ZNF76 Ovarian cancer (OV) is the 7th most common cancer in women, with an estimated 239 000 new cases and 152 000 deaths worldwide annually [ 1 ]. The majority...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (12): BSR20212218.
Published: 07 December 2021
... and the Biochemical Society under a transformative agreement with JISC. bioinformatics biomarkers breast cancer master regulators surfaceome transcriptomics While advances in therapeutic options and diagnostic tools have significantly improved breast cancer (BRCA) survival, BRCA incidence has...
Includes: Supplementary data
Articles
Articles
Biosci Rep (2021) 41 (10): BSR20211615.
Published: 12 October 2021
... 09 2021 20 09 2021 © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . bioinformatics Brain metastasis tumor...
Articles
Biosci Rep (2021) 41 (7): BSR20210158.
Published: 28 July 2021
... of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . bioinformatics Head and neck cancer Immune Prognosis Tumor environment GSEA was employed to identify the underlying biological functions and pathways of high- and low-FOXD1 expression groups...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (7): BSR20204301.
Published: 01 July 2021
... activity (MF). Furthermore, according to the KEGG pathway analysis, the cytokine–cytokine receptor interaction pathway was markedly enriched ( Figure 2 D). The top ten pathways of DEIRGs are listed in Supplementary Table S2. Correspondence: Ke Xu ( xuke@cmc.edu.cn ) bioinformatics immune...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (7): BSR20210033.
Published: 01 July 2021
...Nese Unver The patterns of chemokine expression play a decisive role in both breast cancer prognosis and metastasis. In a recent article published in Bioscience Reports , ‘Bioinformatics identification of CCL8/21 as potential prognostic biomarkers in breast cancer microenvironment’, Chen et al...
Articles
Articles
Biosci Rep (2021) 41 (5): BSR20210231.
Published: 21 May 2021
... and distributed under the Creative Commons Attribution License 4.0 (CC BY) . bioinformatics DLGAP5 glioma LMNB1 prognosis proliferation Glioma is the most common primary cancer in the central nervous system. The 5-year survival rate of glioma patients is poor due to the invasive growth...
Articles
Articles
Biosci Rep (2021) 41 (3): BSR20203235.
Published: 17 March 2021
... ) 09 09 2020 24 02 2021 09 03 2021 09 03 2021 © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Bioinformatics...
Articles
Biosci Rep (2021) 41 (1): BSR20203458.
Published: 12 January 2021
... DNA-binding transcription activator activity ( Figure 3 A). KEGG analysis revealed the most enriched pathways including mitogen-activated protein kinase (MAPK) pathway, senescence, and TGF-beta signaling pathway ( Figure 3 B). bioinformatics diagnostic indicator serum miRNAs stroke WGCNA...
Articles
Articles
Biosci Rep (2021) 41 (1): BSR20203459.
Published: 07 January 2021
... BY) . bioinformatics cancer tumor Thyroid cancer is not only the most common malignancy of the human endocrine system, accounting for ∼3% of the total incidence of systemic malignant tumors, but also one of the fastest growing malignant solid tumors. According to the histopathological classification system...
Articles
Biosci Rep (2021) 41 (1): BSR20203204.
Published: 06 January 2021
... 27 11 2020 © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . abdominal aortic aneurysm bioinformatics FRZB gene expression...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (11): BSR20201820.
Published: 17 November 2020
... article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . bioinformatics cancer immunology microRNA Correspondence: Riyue Yu ( yu-riyue@bjsjth.cn ) 30 05 2020 26 10 2020 27...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (10): BSR20201012.
Published: 28 October 2020
... an immune-related gene (IRG) prognostic model in STAD using bioinformatics analysis. Methods: RNA sequencing data from healthy samples and samples with STAD, IRGs, and transcription factors were analyzed. The hub IRGs were identified using univariate and multivariate Cox regression analyses. Using the hub...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (10): BSR20200980.
Published: 13 October 2020
... (CC BY) . Bioinformatics CIBERSORT Differentially expressed genes Stomach adenocarcinoma Tumor microenvironment Stomach adenocarcinoma (STAD) is one of the most gastrointestinal malignancies, ranking the fifth in cancer incidence and the third in cancer mortality worldwide. Although...
Includes: Supplementary data
Articles
Articles
Biosci Rep (2020) 40 (9): BSR20193995.
Published: 16 September 2020
... potential clues and scientific evidence for further studies using bioinformatics tools [ 14 ]. In the present study, the gene expression profile of GSE34198 and the miRNA expression profiles of GSE61741 and GSE31568 were obtained from the Gene Expression Omnibus (GEO) [ 15–17 ]. The limma package and metaMA...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (9): BSR20202346.
Published: 16 September 2020
...). 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Bioinformatics Computational biology Pulmonary Arterial Hypertension Transcriptomics Pulmonary...
Articles
Biosci Rep (2020) 40 (8): BSR20200894.
Published: 28 August 2020
...Kaifei Zhao; Lin Xu; Feng Li; Jin Ao; Guojun Jiang; Rongshu Shi; Fang Chen; Qing Luo Background: Due to the heterogeneity of hepatocellular carcinoma (HCC), hepatocelluarin-associated differentially expressed genes were analyzed by bioinformatics methods to screen the molecular markers for HCC...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (8): BSR20200963.
Published: 20 August 2020
... 14 08 2020 14 08 2020 © 2020 The Author(s). 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . bioinformatics biomarker hub genes overall...
Includes: Supplementary data
Articles
Articles
Biosci Rep (2020) 40 (8): BSR20201555.
Published: 17 August 2020
...). 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . bioinformatics key gene papillary thyroid carcinoma RNA-Seq Thyroid carcinoma is presently...
Articles
Biosci Rep (2020) 40 (8): BSR20201261.
Published: 07 August 2020
... License 4.0 (CC BY) . bioinformatics biological function hub genes Ovarian cancer prognostic model Ovarian cancer (OC) is the most lethal malignant disease in the female reproductive system, with over 200000 new cases and 150000 deaths each year worldwide [ 1 ]. Epithelial OC accounts...
Includes: Supplementary data
Articles
Articles
Biosci Rep (2020) 40 (7): BSR20201083.
Published: 21 July 2020
... by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . bioinformatics peroxisome proliferator-activated receptors psychotic disorders Schizophrenia (SCZ) is a mental illness with high heritability...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (6): BSR-20181016_COR.
Published: 19 June 2020
... prognosis bioinformatics The authors of the original article above article “The effect of HMGB1 on the clinicopathological and prognostic features of cervical cancer” ( Bioscience Reports (2019) 39 , https://doi.org/10.1042/BSR20181016 ) would like to correct Figure 2 A, as the survivor curves...
Articles
Biosci Rep (2020) 40 (5): BSR20193377.
Published: 27 May 2020
... of WGCNA package gradually in bioinformatics due to the fact that the algorithm is more reliable than the conventional linear regression analysis and also applicable to the analysis of large sample size. Even more, some co-expression phenomena obtained through this algorithm can even predict binding sites...
Articles
Biosci Rep (2020) 40 (3): BSR20194255.
Published: 27 March 2020
...). 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . bioinformatics expression glioma prognosis WNT Glioma represents the most frequent primary...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (3): BSR20200298.
Published: 20 March 2020
... in the cytokine production, a series Cytokine Antibody Arrays were performed to detect differentially expressed cytokines between control and HIP-55 knockdown cells. A total of 97 differentially expressed cytokines were identified from 300 cytokines in A549 cell. Bioinformatics analysis showed...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (2): BSR20192724.
Published: 25 February 2020
..., survival status, and survival duration in months were downloaded from from cBioPortal for Cancer Genomics ( http://www.cbioportal.org/ ). According to the publication guidelines, datasets may be used for publication without restriction or limitation. Bioinformatics Head and neck cancer Immune...
Includes: Supplementary data
Articles
Articles
Biosci Rep (2019) 39 (7): BSR20191612.
Published: 29 July 2019
..., we utilized bioinformatics approaches to identify differentially expressed genes (DEGs) between HNSCC tissues and normal controls from three independent GEO datasets. Then, we selected PYGM and TNCC2, both were not investigated in HNSCC before, to evaluate their relative expression and the potential...
Articles
Biosci Rep (2019) 39 (5): BSR20182172.
Published: 31 May 2019
...-like receptor (NLR) signaling pathway. qPCR showed the same expression trend of hub gene ACLY as in our bioinformatics analysis. Conclusion : Bioinformatics analysis revealed that ACLY and the pathways involved are possible target in the molecular mechanism of type 2 diabetes...
Articles
Biosci Rep (2019) 39 (5): BSR20181514.
Published: 17 May 2019
... circRNAs between the tumour tissues and paracancerous tissues of three osteosarcoma patients. Bioinformatics analysis was used to analyse their potential functions. Five differentially expressed circRNAs were selected to detect the relative expression level in tumour and paracancerous tissues of ten...
Includes: Supplementary data
Articles
Biosci Rep (2019) 39 (5): BSR20182109.
Published: 14 May 2019
... – 3516 10.1158/1538-7445.AM2016-3516 28. Xing Z. , Zhang Y. , Zhang X. et al . ( 2013 ) Fangchinoline induces G1 transforming growth factor β-1ation . Phytother. Res. 27 , 1790 – 1794 10.1002/ptr.4936 23401195 bioinformatics colon cancer cell apoptosis cell...
Articles
Articles
Articles
Biosci Rep (2018) 38 (6): BSR20181178.
Published: 07 December 2018
.... 17 07 2018 31 10 2018 06 11 2018 09 11 2018 © 2018 The Author(s). 2018 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . bioinformatics...
Includes: Supplementary data
Articles
Biosci Rep (2018) 38 (2): BSR20171208.
Published: 21 March 2018
... in vascular endothelial injury. It is an important factor in the development of diabetes mellitus (DM). The aim of the present study was to screen out the potential candidate microRNAs (miRNAs) in DM patients with BSS by high-throughput sequencing (HTS) and bioinformatics analysis. Human umbilical vein...
Articles
Biosci Rep (2017) 37 (5): BSR20170844.
Published: 17 October 2017
..., p53, and c-Jun N-terminal kinase) to induce a cure set of stereotyped responses, such as inflammation. Our bioinformatics analysis is consistent with this finding to some extent. Therefore, TLR-9 may activate the NF-κB pathway and thereby contributes to inflammation, a main manifestation of OA...