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Keywords: Atherosclerosis
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Biosci Rep (2022) 42 (7): BSR20212355.
Published: 15 July 2022
... as novel medicines. miRNA have emerged as an important class of RNA master regulators with important roles identified in the pathogenesis of atherosclerotic cardiovascular disease. Atherosclerosis is characterized by a chronic inflammatory build-up, driven largely by low-density lipoprotein cholesterol...
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Biosci Rep (2022) 42 (7): BSR20220583.
Published: 01 July 2022
... as environmental factors. Recent evidence suggests that the oral microbiome has a significant role in triggering atherosclerosis. The present study assessed the oral microbiome composition variation between coronary patients and healthy subjects in order to identify a potential pathogenic signature associated...
Includes: Supplementary data
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Biosci Rep (2022) 42 (5): BSR20211775.
Published: 04 May 2022
... atherosclerosis endothelial dysfunction miR335-5p SIRT7 Atherosclerotic cardiovascular disease (ASCVD), which involves stroke, myocardial infarction and sudden cardiac death, is currently one of the leading causes of global morbidity and mortality [ 1 ]. As expected, the prevalence of ASCVD increases...
Includes: Supplementary data
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Biosci Rep (2022) 42 (5): BSR-2019-3267_COR.
Published: 04 May 2022
... © 2022 The Author(s). 2022 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Atherosclerosis CXCL12 foam cell macrophage The authors...
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Biosci Rep (2021) 41 (10): BSR20211429.
Published: 12 October 2021
...Hao Xu; Tianqing Zhang; Ling He; Mengxia Yuan; Xiao Yuan; Shanshan Wang Objective: To explore the mechanism of Danggui Buxue Decoction (DGBXD) in regulating Atherosclerosis (AS) network based on integrated pharmacological methods. Methods: The active ingredients and targets of DGBXD are obtained...
Includes: Supplementary data
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Biosci Rep (2021) 41 (8): BSR-2018-1852_RET.
Published: 24 August 2021
... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Arterial injury Atherosclerosis Atherosclerotic inflammation Diabetes miR...
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Biosci Rep (2021) 41 (8): BSR-2020-1366_RET.
Published: 05 August 2021
... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . atherosclerosis miR-200a nrf2 piceatannol pyroptosis This article...
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Biosci Rep (2021) 41 (8): BSR20211060.
Published: 05 August 2021
... is necessary to understand the redox biology of age-related diseases. Methods: The fractions of the reduced form (red-), reversible oxidized form (roxi-), and irreversibly oxidized form (oxi-) apoE in serum, obtained from the patients with no apparent disease (controls, n =192) and with atherosclerosis...
Includes: Supplementary data
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Biosci Rep (2020) 40 (9): BSR20201366.
Published: 16 September 2020
...Zhongyuan Mu; Hongling Zhang; Peng Lei As a major bioactive compound from grapes, piceatannol (PIC) has been reported to exert anti-atherosclerotic activity in various studies. Nevertheless, the mechanism underlying the effect of piceatannol against atherosclerosis (AS) is elusive. Our study...
Includes: Supplementary data
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Biosci Rep (2020) 40 (8): BSR20200026.
Published: 20 August 2020
...Daniela Pirri; Maria Fragiadaki; Paul C. Evans Atherosclerosis is a major cause of mortality worldwide and is driven by multiple risk factors, including diabetes. Diabetes is associated with either an insulin deficiency in its juvenile form or with insulin resistance and obesity in Type 2 diabetes...
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Biosci Rep (2020) 40 (1): BSR20193267.
Published: 17 January 2020
...Lingxing Li; Zhenlan Du; Bing Rong; Dapeng Zhao; Aiping Wang; Yuzhen Xu; Huanyi Zhang; Xue Bai; Jingquan Zhong Background: Atherosclerosis (AS) is a chronic inflammatory disease that contributes to multiple cardiovascular diseases (CVDs), and foam cell formation plays important roles...
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Biosci Rep (2019) 39 (7): BSR20190855.
Published: 26 July 2019
...Yibing Zhang; Rui Xu; Xiangjun Li; Qi Tan; Peng Huang; Yang Zhang; Meng Qin; Liqun Ren Objective : The beneficial effects of icariin (ICA) in ameliorating atherosclerosis (AS) are well known, but the underlying protective mechanism has not been fully elucidated. The present study aimed...
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Biosci Rep (2019) 39 (7): BSR20181852.
Published: 02 July 2019
... the Creative Commons Attribution License 4.0 (CC BY) . Atherosclerotic inflammation Atherosclerosis Arterial injury Diabetes miR-15a-5p Diabetes is a common disease that can lead to a higher risk of cardiovascular disease (CVD) and certain severe polyvascular complications, including...
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Biosci Rep (2019) 39 (4): BSR20181783.
Published: 02 April 2019
...Qinshuo Zhao; Dating Sun; Yuanyuan Li; Jin Qin; JiangTao Yan Hypoxia may cause abnormal proliferation and migration of the vascular smooth muscle cells (VSMCs) from the media to the intima. This contributes to vessel narrowing and accelerates the process of atherosclerosis. The association...
Includes: Supplementary data
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Biosci Rep (2018) 38 (3): BSR20180283.
Published: 12 June 2018
...Jing Wang; Yuzhi Bai; Xia Zhao; Jing Ru; Ning Kang; Tian Tian; Liying Tang; Yun An; Pei Li Atherosclerosis develops as a consequence of inflammation and cell senescence. In critical factors involved in the atherosclerotic changes, reactive oxygen species (ROS) generation is considered a leading...
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Biosci Rep (2017) 37 (6): BSR20171104.
Published: 05 December 2017
...Seidu A. Richard; Marian Sackey; Zhaoliang Su; Huaxi Xu Stroke is a major cause of mortality and disability worldwide. Stroke is a frequent and severe neurovascular disorder. The main cause of stroke is atherosclerosis, and the most common risk factor for atherosclerosis is hypertension. Therefore...
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Biosci Rep (2017) 37 (4): BSR20170680.
Published: 07 July 2017
...Zhengzhang Li; Zhe Shen; Haoping Xue; Shi Cheng; Qun Ji; Yutan Liu; Xiangjun Yang Atherosclerosis is a chronic inflammatory disease of the vascular wall. Dysfunction of cystic fibrosis transmembrane conductance regulator (CFTR) has been shown to result in inflammatory responses in cystic fibrosis...
Includes: Supplementary data
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Biosci Rep (2017) 37 (2): BSR20160611.
Published: 15 March 2017
... even after glucose normalization. Increasing evidence shows that epigenetic mechanisms may play a substantial role in the pathophysiology of diabetes and its associated vascular complications, including atherosclerosis, diabetic cardiomyopathy (DCM), nephropathy and retinopathy. In this review, we...
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Biosci Rep (2017) 37 (2): BSR20160244.
Published: 02 March 2017
...GuoHua Ma; Bing Pan; Yue Chen; CaiXia Guo; MingMing Zhao; LeMin Zheng; BuXing Chen Several studies have reported a strong association between high plasma level of trimethylamine N-oxide (TMAO) and atherosclerosis development. However, the exact mechanism underlying this correlation is unknown...
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Biosci Rep (2008) 28 (3): 145–151.
Published: 30 July 2008
...), supplemented with 10% (v/v) fetal calf serum, 2 mM glutamine, 10 μg/ml streptomycin and 10 units/ml penicillin, in a 5% CO 2 /95% air atmosphere at 37°C. atherosclerosis CD36 endocytosis human embryonic kidney cell (HEK-293 cell) mutagenesis oxidized low-density lipoprotein (OxLDL) Figure...
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Biosci Rep (2001) 21 (5): 667–681.
Published: 01 October 2001
... significantly. These data suggested that changes in transmembrane Ca 2+ gradients might be involved in the apoptosis of macrophages induced by OxLDL. © 2001 Plenum Publishing Corporation 2001 Apoptosis necrosis macrophage OxLDL transmembrane Ca 2+ gradient atherosclerosis Bioscience Reports...
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Biosci Rep (2000) 20 (1): 1–12.
Published: 01 February 2000
... inducethe up-regulation of scavenger receptor in macrophages, resulting inthe formation of foam cells. © 2000 Plenum Publishing Corporation 2000 Transmembrane Ca 2+ adient Macrophage-derived foam cell Scavenger receptor Atherosclerosis Bioscience Reports, Vol. 20, No. 1, 2000 Changes...