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Keywords: 5 fluorouracil
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Articles
Combined in silico and 19 F NMR analysis of 5-fluorouracil metabolism in yeast at low ATP conditions
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (12): BSR20192847.
Published: 10 December 2019
...Piotr H. Pawłowski; Paweł Szczęsny; Bożenna Rempoła; Anna Poznańska; Jarosław Poznański The cytotoxic effect of 5-fluorouracil (5-FU) on yeast cells is thought to be mainly via a misincorporation of fluoropyrimidines into both RNA and DNA, not only DNA damage via inhibition of thymidylate synthase...
Includes: Supplementary data
