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July 2022
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Cover Image
Cover Image
The cover of this issue of Bioscience Reports (volume 42, issue 7) features a representation of the human CFTR 3D structure, illustrating striking features of the channel. The two ATP molecules are shown at the interface between NBD1 and NBD2. Transmembrane (TM) helices extend in the cytoplasm, forming long intracellular loops (ICLs) which contact the NBDs through coupling helices. Find out more in the review article by Farinha and Callebaut.
ISSN 0144-8463
EISSN 1573-4935
Review Articles
Molecular mechanisms of cystic fibrosis – how mutations lead to misfunction and guide therapy
Biosci Rep (2022) 42 (7): BSR20212006.
Emerging concepts in designing next-generation multifunctional nanomedicine for cancer treatment
Biosci Rep (2022) 42 (7): BSR20212051.
Research Articles
Andrographolide in atherosclerosis: integrating network pharmacology and in vitro pharmacological evaluation
Shuai Shi; Xinyu Ji; Jingjing Shi; Shuqing Shi; Fei She; Qiuyan Zhang; Yu Dong; Hanming Cui; Yuanhui Hu
Biosci Rep (2022) 42 (7): BSR20212812.
A potential oral microbiome signature associated with coronary artery disease in Tunisia
Fériel Bouzid; Imen Gtif; Suad Alfadhli; Salma Charfeddine; Walid Ghorbel; Rania Abdelhédi; Riadh Benmarzoug; Leila Abid; Nouha Bouayed Abdelmoula; Inés Elloumi; Saber Masmoudi; Ahmed Rebai; Najla Kharrat
Biosci Rep (2022) 42 (7): BSR20220583.
Cryptic in vitro ubiquitin ligase activity of HDMX towards p53 is probably regulated by an induced fit mechanism
Karla Gisel Calderon-González; Ixaura Medina-Medina; Lucia Haronikova; Lenka Hernychova; Ondrej Bonczek; Lukas Uhrik; Vaclav Hrabal; Borivoj Vojtesek; Robin Fahraeus; Jesús Hernández-Monge; Vanesa Olivares-Illana
Biosci Rep (2022) 42 (7): BSR20220186.
Rbfox1 expression in amacrine cells is restricted to GABAergic and VGlut3 glycinergic cells
Biosci Rep (2022) 42 (7): BSR20220497.
EFR3 and phosphatidylinositol 4-kinase IIIα regulate insulin-stimulated glucose transport and GLUT4 dispersal in 3T3-L1 adipocytes
Anna M. Koester; Angéline Geiser; Kamilla M.E. Laidlaw; Silke Morris; Marie F.A. Cutiongco; Laura Stirrat; Nikolaj Gadegaard; Eckhard Boles; Hannah L. Black; Nia J. Bryant; Gwyn W. Gould
Biosci Rep (2022) 42 (7): BSR20221181.
Gene expression profile associated with Asmt knockout-induced depression-like behaviors and exercise effects in mouse hypothalamus
Biosci Rep (2022) 42 (7): BSR20220800.
Interacting partners of Brassica juncea regulator of G-protein signaling protein suggest its role in cell wall metabolism and cellular signaling
Biosci Rep (2022) 42 (7): BSR20220302.
INK4 cyclin-dependent kinase inhibitors as potential prognostic biomarkers and therapeutic targets in hepatocellular carcinoma
Biosci Rep (2022) 42 (7): BSR20221082.
Possible regulation of Toll-like receptor 4 by lysine acetylation through LPCAT2 activity in RAW264.7 cells
Biosci Rep (2022) 42 (7): BSR20220251.
Whole-genome survey and phylogenetic analysis of Gadus macrocephalus
Biosci Rep (2022) 42 (7): BSR20221037.
TCF7 is highly expressed in immune cells on the atherosclerotic plaques, and regulating inflammatory signaling via NFκB/AKT/STAT1 signaling
Zhongnan Ma; Chuang Wang; Xiufeng Bai; Long Wang; Qianjing Wu; Zehong Cai; Wanxiang Wang; Zhuo Ma; Xinyu Liu; Jiaxuan Feng; Rui Feng
Biosci Rep (2022) 42 (7): BSR20212064.
Exploring mechanisms of Chaihu-Shugan-San against liver fibrosis by integrated multi-omics and network pharmacology approach
Biosci Rep (2022) 42 (7): BSR20221030.
A robust immune-related lncRNA signature for the prognosis of human colorectal cancer
Biosci Rep (2022) 42 (7): BSR20220078.
TTN mutations predict a poor prognosis in patients with thyroid cancer
Biosci Rep (2022) 42 (7): BSR20221168.
Insecticidal efficacy of nanomaterials used to control mosquito, Culex quinquefasciatus Say, 1823 with special reference to their hepatotoxicity in rats
Biosci Rep (2022) 42 (7): BSR20220630.
Differential expression profile of mRNAs, lncRNAs, and circRNAs reveals potential molecular mechanism in breast cancer
Biosci Rep (2022) 42 (7): BSR20220645.
Corrections
Correction: The effects of myeloablative or non-myeloablative total body irradiations on intestinal tract in mice
Biosci Rep (2022) 42 (7): BSR-2020-2993_COR.
Retractions
Retraction: Hsa_circ_0000673 is down-regulated in gastric cancer and inhibits the proliferation and invasion of tumor cells by targeting miR-532-5p
Biosci Rep (2022) 42 (7): BSR-2018-0538_RET.
Expression of Concern
Expression of Concern: Long noncoding RNA HOXA-AS2 promotes non-small cell lung cancer progression by regulating miR-520a-3p
Biosci Rep (2022) 42 (7): BSR-2019-0283_EOC.
Expression of Concern: Dexmedetomidine postconditioning suppresses myocardial ischemia/reperfusion injury by activating the SIRT1/mTOR axis
Biosci Rep (2022) 42 (7): BSR-2019-4030_EOC.
