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February 2022
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In this issue of Bioscience Reports (volume 42, issue 2), Adam and Sohl discuss enzyme activity in cancer. Residue D273 (highlighted in blue or green in each monomer) of dimeric human isocitrate dehydrogenase 1 (IDH1) appears to help sense local changes in pH, presumably via a change in ionization state that affects the 3D structure of IDH1. Interestingly, this residue is buried in the dimer interface, > 9 angstroms from the nearest substrate.Close Modal
ISSN 0144-8463
EISSN 1573-4935
In this Issue
Review Articles
Probing altered enzyme activity in the biochemical characterization of cancer
Biosci Rep (2022) 42 (2): BSR20212002.
Mycobacterium tuberculosis carbon and nitrogen metabolic fluxes
Biosci Rep (2022) 42 (2): BSR20211215.
Current progress of immune checkpoint inhibitors in the treatment of advanced hepatocellular carcinoma
Biosci Rep (2022) 42 (2): BSR20212304.
Lassa virus glycoprotein complex review: insights into its unique fusion machinery
Biosci Rep (2022) 42 (2): BSR20211930.
Research Articles
Identification of potential immunotherapy biomarkers for breast cancer by bioinformatics analysis
Biosci Rep (2022) 42 (2): BSR20212035.
The anti-tumor effects of the combination of microwave hyperthermia and lobaplatin against breast cancer cells in vitro and in vivo
Xiaohu Li; Xin Zhang; Inam Ullah Khan; Nina N. Guo; Bing Wang; Yifeng Guo; Bufan Xiao; Yueshan Zhang; Yimin Chu; Junsong Chen; Fang Guo
Biosci Rep (2022) 42 (2): BSR20190878.
Role of ACSL4 in the chemical-induced cell death in human proximal tubule epithelial HK-2 cells
Biosci Rep (2022) 42 (2): BSR20212433.
Identify potential prognostic indicators and tumor-infiltrating immune cells in pancreatic adenocarcinoma
Biosci Rep (2022) 42 (2): BSR20212523.
IGF2BP2 maybe a novel prognostic biomarker in oral squamous cell carcinoma
Biosci Rep (2022) 42 (2): BSR20212119.
XSSJS inhibits hepatic fibrosis by promoting the miR-29b-3p/VEGFA axis in vitro and in vivo
Biosci Rep (2022) 42 (2): BSR20212241.
