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February 2019
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Cover Image
Cover Image
Drosophila larval salivary glands of varying Drosophila phosphatidylinositol 5 phosphate 4-kinase (dPIP4K) activity, stained with fluorescent dyes to outline individual cells and their membranes. In the latest issue of Bioscience Reports (volume 39, issue 2), Mathre et al. suggest that the size of larval salivary gland cells is regulated by multiple cell signalling mechanisms, including lipid based second messengers. Discovery of dPIP4K mechanisms in Drosophila may suggest novel therapeutic applications using the human isoform PIP4K in humans.
ISSN 0144-8463
EISSN 1573-4935
In this Issue
Review Articles
Computational modeling of RNA 3D structure based on experimental data
Almudena Ponce-Salvatierra; Astha; Katarzyna Merdas; Chandran Nithin; Pritha Ghosh; Sunandan Mukherjee; Janusz M. Bujnicki
Biosci Rep (2019) 39 (2): BSR20180430.
AMPK is associated with the beneficial effects of antidiabetic agents on cardiovascular diseases
Biosci Rep (2019) 39 (2): BSR20181995.
Commentaries
Role of mast cells in the generation of a T-helper type 2 dominated anti-helminthic immune response
Biosci Rep (2019) 39 (2): BSR20181771.
Research Articles
Serum profile of cytokines and their genetic variants in metabolic syndrome and healthy subjects: a comparative study
Biosci Rep (2019) 39 (2): BSR20181202.
p16INK4a inhibits the proliferation of osteosarcoma cells through regulating the miR-146b-5p/TRAF6 pathway
Biosci Rep (2019) 39 (2): BSR20181268.
Association of IL-6, IL-8, MMP-13 gene polymorphisms with knee osteoarthritis susceptibility in the Chinese Han population
Biosci Rep (2019) 39 (2): BSR20181346.
MiR-384 induces apoptosis and autophagy of non-small cell lung cancer cells through the negative regulation of Collagen α-1(X) chain gene
Biosci Rep (2019) 39 (2): BSR20181523.
Treatment of clinical T4 stage superior sulcus non-small cell lung cancer: a propensity-matched analysis of the surveillance, epidemiology, and end results database
Junmiao Wen; Di Liu; Donglai Chen; Jiayan Chen; Xinyan Xu; Chang Chen; Fuquan Zhang; Shanzhou Duan; Rongying Zhu; Min Fan; Yongbing Chen
Biosci Rep (2019) 39 (2): BSR20181545.
Association among cytotoxic T-lymphocyte antigen 4 gene, rs231775 polymorphism, and recurrent pregnancy loss risk
Biosci Rep (2019) 39 (2): BSR20181760.
The effects of novel α2-adrenoreceptor agonist dexmedetomidine on shivering in patients underwent caesarean section
Biosci Rep (2019) 39 (2): BSR20181847.
Bronchial epithelial cells of young and old mice directly regulate the differentiation of Th2 and Th17
Da Liu; Long He; Ning Ding; Wenjin Sun; Lulu Qiu; Li Xu; Aijun Jia; Cong Peng; Dongshan Zhang; Xudong Xiang
Biosci Rep (2019) 39 (2): BSR20181948.
Knockdown of Rab7a suppresses the proliferation, migration, and xenograft tumor growth of breast cancer cells
Biosci Rep (2019) 39 (2): BSR20180480.
Cystatin C for predicting all-cause mortality and rehospitalization in patients with heart failure: a meta-analysis
Biosci Rep (2019) 39 (2): BSR20181761.
Tumor necrosis factor gene polymorphisms are associated with silicosis: a systemic review and meta-analysis
Biosci Rep (2019) 39 (2): BSR20181896.
The proliferation and invasion of osteosarcoma are inhibited by miR-101 via targetting ZEB2
Biosci Rep (2019) 39 (2): BSR20181283.
Synaptotagmin-7, a binding protein of P53, inhibits the senescence and promotes the tumorigenicity of lung cancer cells
Biosci Rep (2019) 39 (2): BSR20181298.
Association between the estrogen receptor α gene polymorphisms rs2234693 and rs9340799 and severe and mild pre-eclampsia: a meta-analysis
Biosci Rep (2019) 39 (2): BSR20181548.
Endoplasmic reticulum stress is involved in spiral ganglion neuron apoptosis following chronic kanamycin-induced deafness
Biosci Rep (2019) 39 (2): BSR20181749.
Modulation of miR-10a-mediated TGF-β1/Smads signaling affects atrial fibrillation-induced cardiac fibrosis and cardiac fibroblast proliferation
Biosci Rep (2019) 39 (2): BSR20181931.
Correlations of IL-17 and NF-κB gene polymorphisms with susceptibility and prognosis in acute respiratory distress syndrome in a chinese population
Biosci Rep (2019) 39 (2): BSR20181987.
2,5-Hexanedione mediates neuronal apoptosis through suppression of NGF via PI3K/Akt signaling in the rat sciatic nerve
Biosci Rep (2019) 39 (2): BSR20181122.
Down-regulation of microRNA-34a-5p promotes trophoblast cell migration and invasion via targetting Smad4
Biosci Rep (2019) 39 (2): BSR20181631.
Zinc binding regulates amyloid-like aggregation of GAPR-1
Jie Sheng; Nick K. Olrichs; Willie J. Geerts; Xueyi Li; Ashfaq Ur Rehman; Barend M. Gadella; Dora V. Kaloyanova; J. Bernd Helms
Biosci Rep (2019) 39 (2): BSR20182345.
Chemoprotective effects of butanol fraction of Buchholzia coriacea (Capparidaceae) against type 2 diabetes and oxidative stress in male Wistar rats
Biosci Rep (2019) 39 (2): BSR20170665.
Nupr1 regulates palmitate-induced apoptosis in human articular chondrocytes
Biosci Rep (2019) 39 (2): BSR20181473.
Percutaneous endoscopic transforaminal discectomy precedes interlaminar discectomy in the efficacy and safety for lumbar disc herniation
Biosci Rep (2019) 39 (2): BSR20181866.
C-reactive protein for predicting all-cause mortality in patients with acute ischemic stroke: a meta-analysis
Biosci Rep (2019) 39 (2): BSR20181135.
Autophagy induced by SAHA affects mutant P53 degradation and cancer cell survival
Giorgia Foggetti; Laura Ottaggio; Debora Russo; Carlotta Mazzitelli; Paola Monti; Paolo Degan; Mariangela Miele; Gilberto Fronza; Paola Menichini
Biosci Rep (2019) 39 (2): BSR20181345.
Plasma lipidomic profiling in murine mutants of Hermansky–Pudlak syndrome reveals differential changes in pro- and anti-atherosclerotic lipids
Biosci Rep (2019) 39 (2): BSR20182339.
Association between the ICAM-1 gene polymorphism and coronary heart disease risk: a meta-analysis
De-lu Yin; Xin-hua Zhao; Yi Zhou; Ying Wang; Ping Duan; Qun-xing Li; Zheng Xiong; Yang-yang Zhang; Yu Chen; Hong He; Kai Yang; He-jian Song
Biosci Rep (2019) 39 (2): BSR20180923.
Characterization of recombinant fructose-1,6-bisphosphatase gene mutations: evidence of inhibition/activation of FBPase protein by gene mutation
Gemma Topaz; Victor Epiter-Smith; Cristina Robalo; Megan Emad; Vanessa Ford; Jadine Daley; Jennifer Byron; Kimberly A. Stieglitz
Biosci Rep (2019) 39 (2): BSR20180960.
Metabolomic analysis reveals a protective effect of Fu-Fang-Jin-Qian-Chao herbal granules on oxalate-induced kidney injury
Wei Chen; Wen-Rui Liu; Jie-Bin Hou; Jia-Rong Ding; Zhong-Jiang Peng; Song-Yan Gao; Xin Dong; Jun-Hua Ma; Qi-Shan Lin; Jian-Rao Lu; Zhi-Yong Guo
Biosci Rep (2019) 39 (2): BSR20181833.
Bioinformatics analysis to identify the key genes affecting the progression and prognosis of hepatocellular carcinoma
Biosci Rep (2019) 39 (2): BSR20181845.
Specific and rapid identification of the Pheretima aspergillum by loop-mediated isothermal amplification
Biosci Rep (2019) 39 (2): BSR20181943.
The therapeutic effect of switching from tacrolimus to low-dose cyclosporine A in renal transplant recipients with BK virus nephropathy
Xu-Tao Chen; Jun Li; Rong-Hai Deng; Shi-Cong Yang; Yan-Yang Chen; Pei-Song Chen; Ze-Yuan Wang; Yang Huang; Chang-Xi Wang; Gang Huang
Biosci Rep (2019) 39 (2): BSR20182058.
Responses of apoptosis and matrix metabolism of annulus fibrosus cells to different magnitudes of mechanical tension in vitro
Biosci Rep (2019) 39 (2): BSR20182375.
The value of Cone-Beam CT-guided radiofrequency ablation in the treatment of pulmonary malignancies (≤3 cm)
Biosci Rep (2019) 39 (2): BSR20181230.
Overexpression of UHRF1 promoted the proliferation of vascular smooth cells via the regulation of Geminin protein levels
Biosci Rep (2019) 39 (2): BSR20181341.
Association between ACE gene I/D polymorphism and knee osteoarthritis in a Chinese population
Biosci Rep (2019) 39 (2): BSR20181713.
Increase of glandular epithelial cell clusters by an external volume expansion device promotes adipose tissue regeneration by recruiting macrophages
Biosci Rep (2019) 39 (2): BSR20181776.
Acyl-CoA: cholesterol acyltransferases-2 gene polymorphism is associated with increased susceptibility to coronary artery disease in Uygur population in Xinjiang, China
Yong-Tao Wang; Buamina Maitusong; Yi-Tong Ma; Zhen-Yan Fu; Yi-Ning Yang; Xiang Ma; Xiao-Mei Li; Fen Liu; Bang-Dang Chen
Biosci Rep (2019) 39 (2): BSR20182129.
Overexpression of BUB1B, CCNA2, CDC20, and CDK1 in tumor tissues predicts poor survival in pancreatic ductal adenocarcinoma
Biosci Rep (2019) 39 (2): BSR20182306.
Interaction between GDF5 gene polymorphisms and environment factors increased the risk of knee osteoarthritis: a case–control study
Biosci Rep (2019) 39 (2): BSR20182423.
Human G protein-coupled receptor 30 is N-glycosylated and N-terminal domain asparagine 44 is required for receptor structure and activity
Biosci Rep (2019) 39 (2): BSR20182436.
The associations between Toll-like receptor 4 gene polymorphisms and hepatitis C virus infection: a systematic review and meta-analysis
Biosci Rep (2019) 39 (2): BSR20182470.
OPN gene locus is associated with the risk of knee osteoarthritis: a case–control study
Biosci Rep (2019) 39 (2): BSR20182023.
Association between peroxisome proliferator-activated receptor γ-2 gene Pro12Ala polymorphisms and risk of hypertension: an updated meta-analysis
Biosci Rep (2019) 39 (2): BSR20190022.