The authors of the original article “The N-terminus of Paenibacillus larvae C3larvinA modulates catalytic efficiency” (Biosci Rep (2021) 41(1), DOI: 10.1042/BSR20203727) would like to correct Figure 5 of their article. During figure preparation for the submission of their manuscript, there had been an inadvertent duplication of Panel E which resulted in the replacement of Panel F in Figure 5. The authors clarify that Panels E and F were different variants of the C3larvinA toxin that produced identical phenotypes when infecting host macrophages. They further state that this duplication of panel E in Figure 5 does not change the conclusion of the results in Figure 5 or in the paper. The correct Figure 5 is present in this Correction. The authors apologise for any inconvenience caused by this error.
C3larvinA N-terminal deletions have varying effects on the morphology of macrophage cells
J774A.1 mouse macrophage cells were treated with 300 nM toxin and incubated for 20 h at a cell density of 37500 cells/well. Effects to morphology were less dramatic in the larger N-terminal deletions. (A) Buffer control; (B) C3larvinA (full length); (C) ΔY2-A21; (D) ΔY2-D23; (E) ΔY2-K25; (F) ΔY2-D27; (G) ΔY2-A30; (H) ΔY2-K33; (I) ΔY2-W34.
J774A.1 mouse macrophage cells were treated with 300 nM toxin and incubated for 20 h at a cell density of 37500 cells/well. Effects to morphology were less dramatic in the larger N-terminal deletions. (A) Buffer control; (B) C3larvinA (full length); (C) ΔY2-A21; (D) ΔY2-D23; (E) ΔY2-K25; (F) ΔY2-D27; (G) ΔY2-A30; (H) ΔY2-K33; (I) ΔY2-W34.
