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Keywords: zygote
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Biochem Soc Trans (2017) 45 (5): 1117–1124.
Published: 22 September 2017
... in order to establish totipotency in blastomeres of an early embryo. This remodeling involves replacement of maternal RNAs with zygotic RNAs through maternal RNA degradation and zygotic genome activation. This review is focused on expression and function of long noncoding RNAs (lncRNAs) and small RNAs...