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Keywords: virus
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Biochem Soc Trans (2019) 47 (1): 251–264.
Published: 15 January 2019
... occurred in 2009. This ‘Swine Flu’ pandemic was caused by a novel H1N1 virus that was created through numerous reassortment events in swine. Estimates range from 150 000 to nearly 600 000 deaths worldwide [ 29 ]. An example of a possible reassortment event between two influenza viruses is shown in Figure...
Biochem Soc Trans (2018) 46 (3): 691–698.
Published: 21 May 2018
...Joel D. Allen; Rogier W. Sanders; Katie J. Doores; Max Crispin The extensive post-translational modifications of the envelope spikes of the human immunodeficiency virus (HIV) present considerable challenges and opportunities for HIV vaccine design. These oligomeric glycoproteins typically have over...
Biochem Soc Trans (2013) 41 (6): 1416–1421.
Published: 20 November 2013
... interspaced by variable numbers of unique spacers ( Figure 1 B). The majority of spacer sequences are 37 bp in length, but range in size from 34 to 59 bp. The origins of the spacers are unknown as none map to the few currently known Thermococcales viruses or plasmids [ 24 – 27 ]. The P. furiosus repeat RNA...
Biochem Soc Trans (2013) 41 (4): 876–880.
Published: 18 July 2013
... antiviral immunity of plants and animals Virus Res. 2004 102 109 115 20 Obbard D.J. Gordon K.H. J. Buck A.H. Jiggins F.M. The evolution of RNAi as a defence against viruses and transposable elements Philos. Trans. R. Soc. London Ser. B 2009 364 99 115 21 Lu R...
Biochem Soc Trans (2013) 41 (1): 84–88.
Published: 29 January 2013
... to the ER and the Golgi respectively, and their function during capsid formation [ 34 ]. Viruses rely on palmitoylation not only for the entry and the production of virions, but also to evade the host immune system. Kaposi's sarcoma-associated herpes virus encodes a RING finger E3 ubiquitin ligase MIR2...
Biochem Soc Trans (2012) 40 (6): 1409–1415.
Published: 21 November 2012
... that the cellular recycling endosome pathway, in particular Rab11, plays an important role in the assembly of negative-strand RNA viruses such as respiratory syncytial virus, influenza A virus, Andes virus and Sendai virus. The present mini-review discusses this emerging field and explores the potential roles...
Biochem Soc Trans (2011) 39 (2): 524–528.
Published: 22 March 2011
... lymphotrophic virus), CDV (canine distemper virus) and HCV (hepatitis C virus; see [ 13 ] for a detailed review). Viruses are obligate parasites of eukaryotic cells. The life cycle of enveloped viruses necessitates interaction and fusion of the viral lipid envelope with host-cell membranes for virus entry...
Biochem Soc Trans (2011) 39 (1): 36–44.
Published: 19 January 2011
... [ 36 ]. Figure 1 Schematic representation of characterized (pGT5/pTN1) or putative (others) replication cassettes of Thermococcales plasmids, viruses or virus-related region inserted in Thermococcales genomes Homologous genes are drawn with the same colour. Yellow circles represent described...
Biochem Soc Trans (2010) 38 (6): 1602–1607.
Published: 24 November 2010
... life cycles Cell Host Microbe 2008 3 206 212 48 Beckham C.J. Light H.R. Nissan T.A. Ahlquist P. Parker R. Noueiry A. Interactions between brome mosaic virus RNAs and cytoplasmic processing bodies J. Virol. 2007 81 9759 9768 49 Checkley M.A...
Biochem Soc Trans (2010) 38 (1): 50–53.
Published: 19 January 2010
... fungal, bacterial and viral infections. Resveratrol affects a wide variety of viruses, suggesting that this chemical agent interferes with infection by altering cellular pathways rather than acting directly against the virus itself. The activity of resveratrol in protection from viral infection...
Biochem Soc Trans (2009) 37 (4): 665–670.
Published: 22 July 2009
... viruses: implications and applications Adv. Virus Res. 2003 62 167 239 9 Wang Q. Lin T. Tang L. Johnson J.E. Finn M.G. Icosahedral virus particles as addressable nanoscale building blocks Angew. Chem. Int. Ed. 2002 41 459 462 10 Steinmetz N.F...
Biochem Soc Trans (2009) 37 (1): 195–199.
Published: 20 January 2009
... for transport (ESCRT) multivesicular body (MVB) retrovirus tumour susceptibility gene 101 (Tsg101) vacuolar protein sorting 4 (Vps4) virus The ESCRT machinery comprises the protein products of the Class E subset of Vps (vacuolar protein sorting) genes, identified as being required for sorting...
Biochem Soc Trans (2008) 36 (4): 637–639.
Published: 22 July 2008
...Questa H. Karlsson; Celine Schelcher; Elizabeth Verrall; Carlo Petosa; Alison J. Sinclair EBV (Epstein–Barr virus) alternates between latency and lytic replication. During latency, the viral genome is largely silenced by host-driven methylation of CpG motifs and in the switch to the lytic cycle...
In Collection
Biochem Soc Trans (2006) 34 (6): 1151–1154.
Published: 25 October 2006
... virus hybridizing with a human influenza virus to create a highly virulent, as yet unknown, killer, on a scale unseen since the Spanish flu outbreak of 1918, which produced more fatalities than the Great War. In deciding how countries should react to this potential pandemic, individually...
Biochem Soc Trans (2004) 32 (2): 204–208.
Published: 01 April 2004
... that phylogenetic relationships exist between crenarchaeal rudiviruses and the large eukaryal DNA viruses: poxviruses, the African swine fever virus and Chlorella viruses. Sequence patterns at the ends of the linear genome of the lipothrixvirus AFV1 are reminiscent of the telomeric ends of linear eukaryal...
Biochem Soc Trans (2004) 32 (2): 184–187.
Published: 01 April 2004
..., 13, 15 and 38 kb respectively) were cloned in E. coli and their genomes are currently being sequenced (G. Erauso, A. Bidault, M. Le Romancer and D. Prieur, unpublished work). Viruses and VLPs (virus-like-particles) of Thermococcales In the course of this screening, VLPs were also discovered...