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Miranda E. Good, Daniela Begandt, Leon J. DeLalio, Alexander S. Keller, Marie Billaud, Brant E. Isakson
Biochem Soc Trans (2015) 43 (3): 495–501.
Published: 01 June 2015
..., are needed to demonstrate the role of pannexins in various cellular functions. This review focuses on the known roles of Panx1 related to purinergic signalling in the vasculature focusing on post-translational modifications and channel gating mechanisms that may participate in the regulated release of ATP...
Biochem Soc Trans (2014) 42 (6): 1601–1607.
Published: 17 November 2014
...Neil R. Smith; Stephen R. Wedge; Aurelien Pommier; Simon T. Barry There has been significant investment in developing novel therapies to target solid tumour vasculature. Different technical approaches have been utilized with the aim of inhibiting tumour angiogenesis or compromising the function...
Biochem Soc Trans (2014) 42 (1): 89–97.
Published: 23 January 2014
... the blood and the surrounding tissue. The vasculature expresses three cAMP effector proteins: PKA (protein kinase A), CNG (cyclic-nucleotide-gated) ion channels, and the most recently discovered Epacs (exchange proteins directly activated by cAMP). Epacs are a family of GEFs (guanine-nucleotide-exchange...
Biochem Soc Trans (2005) 33 (5): 1049–1052.
Published: 26 October 2005
... 2005 adipocyte adipose tissue innervation obesity vasculature Although currently defined by the WHO (World Health Organization) in terms of excess weight for a given height [ 1 ], obesity is best considered as being an increase in adiposity. Of necessity, this involves an increase...