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Keywords: vascular smooth muscle
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Biochem Soc Trans (2021) 49 (4): 1855–1865.
Published: 04 August 2021
... vasoconstriction and vascular remodelling. Ion channels are key determinants of vascular smooth muscle tone and homeostasis, and four PAH channelopathies ( KCNK3 , ABCC8 , KCNA5 , TRPC6 ) have been identified so far. However, the contribution of ion channels in other forms of PAH, which account for the majority...
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Biochem Soc Trans (2021) 49 (1): 353–363.
Published: 22 February 2021
... of the Biochemical Society 2021 cardiovascular disease microrna phenotype vascular smooth muscle MicroRNAs (miRs) are short, non-coding RNAs that can act as master regulators of cellular function, switching entire pathways on or off through imperfect binding to the 3′ UTR of target mRNAs...
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Biochem Soc Trans (2014) 42 (1): 89–97.
Published: 23 January 2014
...Owain Llŷr Roberts; Caroline Dart The second messenger cAMP plays a central role in mediating vascular smooth muscle relaxation in response to vasoactive transmitters and in strengthening endothelial cell–cell junctions that regulate the movement of solutes, cells and macromolecules between...