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Keywords: valproic acid
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Biochem Soc Trans (2009) 37 (5): 1104–1109.
Published: 21 September 2009
... using a neuropharmacological approach, combined with kinetic, biochemical and molecular biology techniques, demonstrating that chronic administration of three commonly used mood stabilizers (lithium, valproic acid and carbamazepine), at therapeutically relevant doses, selectively target the brain...
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Biochem Soc Trans (2009) 37 (5): 1099–1103.
Published: 21 September 2009
... inositol phosphate myo -inositol phosphoinositide valproic acid Over 20 years ago, the inositol-depletion hypothesis was put forward by Berridge et al. [ 1 , 2 ] in an attempt to explain the therapeutic mechanism of lithium (Li + ), a drug that has been used for the treatment of bipolar...
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Biochem Soc Trans (2009) 37 (5): 1126–1132.
Published: 21 September 2009
...Nicole Terbach; Robin S.B. Williams The anticonvulsant properties of VPA (valproic acid), a branched short-chain fatty acid, were serendipitously discovered in 1963. Since then, therapeutic roles of VPA have increased to include bipolar disorder and migraine prophylaxis, and have more recently been...
Articles
Biochem Soc Trans (2009) 37 (5): 1077–1079.
Published: 21 September 2009
....) and Talvinder Sihra (University College London, U.K.). BD bipolar disorder GSK3 glycogen synthase kinase 3 VPA valproic acid References 1 Calabrese J.R. Overview of patient care issues and treatment in bipolar spectrum and bipolar II disorder J. Clin. Psychiatry 2008 69...
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Articles
Biochem Soc Trans (2004) 32 (5): 799–802.
Published: 26 October 2004
...-mediated growth cone collapse. Li + also causes growth cones to spread; however, a similar effect is seen with two other mood stabilizers, valproic acid and carbamazepine, but without changes in microtubules or axon branching. This common effect of mood stabilizers is mediated by changes in inositol...