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Keywords: vaccinia virus
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Articles

Insights from vaccinia virus into Toll-like receptor signalling proteins and their regulation by ubiquitin: role of IRAK-2

Andrew G. Bowie
Journal: Biochemical Society Transactions
Biochem Soc Trans (2008) 36 (3): 449–452.
DOI: https://doi.org/10.1042/BST0360449
Published: 21 May 2008
... is discussed. Further, I demonstrate how understanding one molecular mechanism whereby vaccinia virus inhibits NF-κB activation has led to a revealing of a key role for IRAK-2 in TRAF-6-mediated NF-κB activation. 1 email agbowie@tcd.ie 16 1 2008 © The Authors Journal compilation © 2008...
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Articles

An arms race: innate antiviral responses and counteracting viral strategies

M. Schröder, A.G. Bowie
Journal: Biochemical Society Transactions
Biochem Soc Trans (2007) 35 (6): 1512–1514.
DOI: https://doi.org/10.1042/BST0351512
Published: 23 November 2007
... 8 2007 © The Authors Journal compilation © 2007 Biochemical Society 2007 antiviral signalling pattern-recognition receptor retinoic-acid-inducible protein I (RIG-I) Toll-like receptor (TLR) vaccinia virus viral immune evasion The initially described ligands for TLRs were...
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