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Keywords: uracil
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Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2009) 37 (1): 65–68.
Published: 20 January 2009
...Bernard A. Connolly Archaeal family-B DNA polymerases interact specifically with uracil and hypoxanthine, stalling replication on encountering these deaminated bases in DNA template strands. The present review describes X-ray structural data which elucidate the mechanism of read-ahead recognition...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2003) 31 (3): 699–702.
Published: 01 June 2003
...B.A. Connolly; M.J. Fogg; G. Shuttleworth; B.T. Wilson Archaeal family-B DNA polymerases possess a novel uracil-sensing mechanism. A specialized pocket scans the template, ahead of the replication fork, for the presence of uracil; on encountering this base, DNA synthesis is stalled. The structural...
