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Keywords: ubiquitin signalling
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Biochem Soc Trans (2023) BST20220880.
Published: 16 January 2023
... and distributed under the Creative Commons Attribution License 4.0 (CC BY) . E2 enzymes protein degradation ubiquitin ubiquitin chains ubiquitin signalling The post-translational modification of proteins by ubiquitin is involved in most cellular processes. The ubiquitin system is most well...
Biochem Soc Trans (2021) 49 (2): 629–644.
Published: 17 March 2021
... Attribution License 4.0 (CC BY) . functional characterization molecular ultrastructure proteasomes ubiquitin proteasome system ubiquitin signalling ubiquitins Proteasomes are large protein complexes that carry out regulated intracellular proteolysis. All eukaryotic cells use proteasomes...
Biochem Soc Trans (2020) 48 (6): 2377–2386.
Published: 10 December 2020
... ubiquitin signalling The endocytic network was initially identified as an important pathway for the internalisation of ligand complexes and the inducible degradation of receptors from the cell surface [ 1 ]. Subsequently, it has emerged that endocytosis is also required for the maintenance...
Biochem Soc Trans (2020) 48 (4): 1737–1750.
Published: 17 July 2020
... and the Biochemical Society under a transformative agreement with CAUL. enzyme activity post-translational modification RBR ubiquitin ligases ubiquitin ligases ubiquitin signalling The post-translational modification of proteins by addition of a single ubiquitin molecule (monoubiquitination...
Biochem Soc Trans (2019) 47 (6): 1949–1962.
Published: 12 December 2019
... by a combination of polyubiquitin chain length, linkage type, numbers of ubiquitin chains per target, and decoration of ubiquitin with other small modifiers. However, many questions remain about how different ubiquitin signals are specifically recognised and transduced by the decoding ubiquitin-binding domains...
Biochem Soc Trans (2017) 45 (1): 183–191.
Published: 15 February 2017
... 9 2016 14 10 2016 24 10 2016 © 2017 The Author(s); published by Portland Press Limited on behalf of the Biochemical Society 2017 structural characterisation ubiquitin ligases ubiquitin signalling Ubiquitination is a mechanism to regulate many cellular processes...
Biochem Soc Trans (2016) 44 (6): 1581–1602.
Published: 02 December 2016
...’, and ‘erasers’ of the Met1 code achieve specificity at the molecular level. In comparison with knowledge of other ubiquitin signals, the Met1 signal is unique in that the enzymes responsible for the assembly, recognition, and disassembly are known. The following sections describe the molecular details...