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Keywords: ubiquitin signalling
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Articles
Biochem Soc Trans (2024) 52 (2): 773–792.
Published: 17 April 2024
... agreement with JISC. DNA damage response DNA synthesis and repair genome integrity post translational modification SUMOylation ubiquitin signalling SUMOylation is a protein post-translational modification whereby SUMOs are covalently attached to target lysine residues. Mature SUMO2...
Articles
Biochem Soc Trans (2023) 51 (1): 353–362.
Published: 16 January 2023
... and distributed under the Creative Commons Attribution License 4.0 (CC BY) . E2 enzymes protein degradation ubiquitin ubiquitin chains ubiquitin signalling The post-translational modification of proteins by ubiquitin is involved in most cellular processes. The ubiquitin system is most well...
Articles
Biochem Soc Trans (2021) 49 (2): 629–644.
Published: 17 March 2021
... Attribution License 4.0 (CC BY) . functional characterization molecular ultrastructure proteasomes ubiquitin proteasome system ubiquitin signalling ubiquitins Proteasomes are large protein complexes that carry out regulated intracellular proteolysis. All eukaryotic cells use proteasomes...
Articles
Biochem Soc Trans (2020) 48 (6): 2377–2386.
Published: 10 December 2020
... ubiquitin signalling The endocytic network was initially identified as an important pathway for the internalisation of ligand complexes and the inducible degradation of receptors from the cell surface [ 1 ]. Subsequently, it has emerged that endocytosis is also required for the maintenance...
Articles
Biochem Soc Trans (2020) 48 (4): 1737–1750.
Published: 17 July 2020
... and the Biochemical Society under a transformative agreement with CAUL. enzyme activity post-translational modification RBR ubiquitin ligases ubiquitin ligases ubiquitin signalling The post-translational modification of proteins by addition of a single ubiquitin molecule (monoubiquitination...
Articles
Biochem Soc Trans (2019) 47 (6): 1949–1962.
Published: 12 December 2019
... by a combination of polyubiquitin chain length, linkage type, numbers of ubiquitin chains per target, and decoration of ubiquitin with other small modifiers. However, many questions remain about how different ubiquitin signals are specifically recognised and transduced by the decoding ubiquitin-binding domains...
Articles
Biochem Soc Trans (2017) 45 (1): 183–191.
Published: 15 February 2017
... responses is a key function of this protein family [ 3 , 7 , 8 ]. structural characterisation ubiquitin ligases ubiquitin signalling RING dimerisation appears to be a requirement for TRIM E3 catalytic activity, and recent biochemical and biophysical studies on three different TRIM ligases...
Articles
Biochem Soc Trans (2016) 44 (6): 1581–1602.
Published: 02 December 2016
... the ε-amino group of a substrate lysine (Lys). inflammation post-translational modification ubiquitin signalling © 2016 The Author(s) 2016 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons...