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Keywords: tumour progression
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Biochem Soc Trans (2016) 44 (2): 333–341.
Published: 11 April 2016
... promotes oligomerization and transphosphorylation of the receptor, leading to the activation of signal transduction [ 1 , 2 ]. cancer c- fms clinical prognostic factors colony-stimulating factor-1 colony-stimulating factor-1 receptor tumour progression In this mini-review, we describe our...
Biochem Soc Trans (2010) 38 (1): 297–300.
Published: 19 January 2010
... as a potential prognostic marker for TGCTs [ 24 ]. 1 To whom correspondence should be addressed (email c.j.hutchison@durham.ac.uk ). 17 8 2009 © The Authors Journal compilation © 2010 Biochemical Society 2010 biomarker cancer lamin stem cell tumour progression Study...
Biochem Soc Trans (2008) 36 (6): 1350–1353.
Published: 19 November 2008
... that lamin A is a putative colonic epithelial stem cell biomarker suggests that the poor outcome associated with lamin A/C-positive tumours may be reflective of a more stem-cell-like phenotype. The present review discusses the link between lamin A expression and tumour progression in one of the commonest...
Biochem Soc Trans (2005) 33 (5): 1135–1136.
Published: 26 October 2005
... in the TIMPs (tissue inhibitor of metalloproteinases 1–3) [ 6 ]. Considering the wealth of data implicating MMP-9 in tumour progression, there is a real need to identify the biological cues ‘driving’ expression of this gene in cancer. At the same time, it must be recognized that since some members...
Biochem Soc Trans (2005) 33 (4): 672–675.
Published: 01 August 2005
... Wnt signalling β-catenin APC colorectal tumorigenesis tumour progression tumour genetics As proposed in the genetic model of colorectal tumorigenesis by Fearon and Vogelstein, sequential mutations in oncogenes and tumour suppressor genes lead to progression from single crypt lesions...