.... In the present paper, we review recent progress in understanding how the p38 MAPK (mitogen-activated protein kinase) signalling pathway participates in the different steps of metastasis. Experimental evidence suggests that tumour cells need to modulate p38 MAPK activity levels to successfully metastasize...

... Society 2011 immunotherapy interleukin (IL) prostate cancer T-cell tumour cell whey acidic protein (WAP) Prostate cancer is the most common cancer affecting men: it is so common that at least 80% of men who reach the age of 80 have localized cancerous lesions [ 1 ]. In many of these men...

...A. Saudemont; K. Okkenhaug; F. Colucci NK cell (natural killer cells) are lymphocytes of innate immunity that kill tumour cells and respond to infections, without prior stimulation. A balance of activating and inhibitory signals regulates NK cell cytotoxicity, but the molecular mechanisms...

... into the tumour, there was a marked decrease (70%) of the tumour growth. This was compared with a decrease of only 32% in tumour size when the same amount of native BSAO was administered. The mechanism of tumour cell death was also determined. When tumours were treated with immobilized BSAO, there was induction...