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Keywords: tumor microenvironments
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Articles
Biochem Soc Trans (2021) 49 (3): 1409–1423.
Published: 08 June 2021
... article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . epithelial-to-mesenchymal transition growth factors metastasis mutation tumor microenvironments wound healing The overwhelming...
Articles
Biochem Soc Trans (2019) 47 (5): 1543–1555.
Published: 11 October 2019
... surface receptors that impact cell behavior. During cancer growth, this bioactive meshwork is remodeled and enriched in newly formed blood vessels, which provide nutrients and oxygen to the growing tumor cells. Remodeling of the tumor microenvironment leads to the formation of bioactive fragments that may...
Articles
Biochem Soc Trans (2019) 47 (1): 273–280.
Published: 15 January 2019
... stages of disease and during treatment, with elevated levels of PMPs a key and relevant marker [ 26 ]. Many reports have shown that these PMPs can release nucleic acids such as miRNA which can also alter the tumor or the local tumor microenvironment. More tantalizing is the ability of PMPs to bind...
Articles
Biochem Soc Trans (2019) 47 (1): 101–108.
Published: 17 December 2018
...Mohammad Zahied Johan; Michael S. Samuel Reciprocal biochemical and biophysical interactions between tumor cells, stromal cells and the extracellular matrix (ECM) result in a unique tumor microenvironment that determines disease outcome. The cellular component of the tumor microenvironment...
Articles
Biochem Soc Trans (2017) 45 (1): 229–236.
Published: 15 February 2017
...Begum Erdogan; Donna J. Webb Cancer-associated fibroblasts (CAFs) are major components of the surrounding stroma of carcinomas that emerge in the tumor microenvironment as a result of signals derived from the cancer cells. Biochemical cross-talk between cancer cells and CAFs as well as mechanical...