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Keywords: trypanosomatid
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Biochem Soc Trans (2005) 33 (5): 972–974.
Published: 26 October 2005
...D.J. Rigden; M. Herman; S. Gillies; P.A.M. Michels Autophagy is the process by which cellular components are directed to and degraded in the vacuole or lysosome and has been studied largely in yeasts. We present here an in silico genomic analysis of trypanosomatid autophagy aimed at highlighting...
Biochem Soc Trans (2005) 33 (6): 1435–1437.
Published: 26 October 2005
... is primarily exerted post-transcriptionally. Here, we use the recently completed genome sequences of three trypanosomatids, Trypanosoma brucei , Trypanosoma cruzi and Leishmania major , in an in silico analysis of their fundamental RNA polymerase complexes. The core complement of Pol II subunits, including...
Biochem Soc Trans (2000) 28 (2): 186–190.
Published: 01 February 2000
... of the effector sites of the Leishmania and yeast enzymes reveals the structural basis for the different effector specificity. Two loops, comprising residues 443–453 and 480–489, adopt very different conformations in the two enzymes, and Lys-453 and His-480 that are a feature of trypanosomatid enzymes provide...