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Keywords: translocation
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Articles
Biochem Soc Trans (2012) 40 (6): 1469–1474.
Published: 21 November 2012
... is the TolA hub protein which forms protein–protein interactions with all other members and also with extrinsic proteins such as colicins A, E1, E2–E9 and N, and the coat proteins of the Ff family of filamentous bacteriophages. In the present paper, we review the role of TolA in the translocation of colicin...
Articles
Biochem Soc Trans (2012) 40 (6): 1475–1479.
Published: 21 November 2012
...Nicholas G. Housden; Colin Kleanthous We are investigating how protein bacteriocins import their toxic payload across the Gram-negative cell envelope, both as a means of understanding the translocation process itself and as a means of probing the organization of the cell envelope and the function...
Articles
Biochem Soc Trans (2012) 40 (6): 1486–1491.
Published: 21 November 2012
... structurally, but not functionally, as a scaffold on the surface of the target cell so that they can be translocated across the outer membrane. During the import into the periplasm, colicins parasitize functionally membrane porins and energy-transducers by mimicking their natural substrates or interacting...
Articles
Biochem Soc Trans (2012) 40 (6): 1534–1538.
Published: 21 November 2012
... g.moore@uea.ac.uk ). 3 8 2012 © 2012 The Authors Journal 2012 colicin intrinsic disorder Tol Ton translocation For many years, it has been axiomatic that the physiological functional states of most proteins are structured. An illustration of this is that most current...
Articles
Biochem Soc Trans (2008) 36 (6): 1409–1413.
Published: 19 November 2008
...Daniel A. Bonsor; Nicola A. Meenan; Colin Kleanthous The translocation of protein toxins into a cell relies on a myriad of protein–protein interactions. One such group of toxins are enzymatic E colicins, protein antibiotics produced by Escherichia coli in times of stress. These proteins subvert...
Articles
Biochem Soc Trans (2007) 35 (4): 767–769.
Published: 20 July 2007
... of the Drosophila homeoprotein Antennapaedia (residues 43–58, commonly named penetratin, RQIKIWFQNRRMKWKK), also provide novel insights into the fundamental mechanisms of translocation across biological membranes. Thus the efficacy of CPP-mediated cargo delivery continues to provide valuable tools for biomedical...
Articles
Biochem Soc Trans (2006) 34 (5): 791–793.
Published: 25 October 2006
... regulates insulin gene expression in part through the activation and translocation of PDX-1 from the nuclear periphery to the nucleoplasm. We have also found that PASK [PAS (Per-Arnt-Sim) kinase], a member of the nutrient-regulated family of protein kinases, is activated in response to glucose challenge...
Articles
Biochem Soc Trans (2005) 33 (6): 1474–1478.
Published: 26 October 2005
... © 2005 The Biochemical Society 2005 helicase molecular motor nucleic acid metabolism nucleotide triphosphatase (NTPase) strand separation translocation Figure 3 The co-operative inchworm model describing streptavidin displacement from a biotinylated oligonucleotide...
Articles
Biochem Soc Trans (2004) 32 (6): 1130–1132.
Published: 26 October 2004
... and interacting with other host components. The IgA proteases are released by the type V secretion pathway, which involves translocation through two membranes and an autolytic, post-translational processing step. Results reported recently throw light on the type V secretion pathway and on the roles...
Articles
Biochem Soc Trans (2004) 32 (5): 733–737.
Published: 26 October 2004
... The Biochemical Society 2004 elongation factor mRNA decoding peptide-bond formation rapid kinetics translocation The ribosome is a macromolecular machine that synthesizes proteins from aa-tRNA (aminoacyl-tRNA) according to the sequence encoded in mRNA. The elongation phase of protein synthesis...