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Biochem Soc Trans (2021) 49 (2): 579–590.
Published: 05 March 2021
...Sebastian L. Wild; David Tosh Transdifferentiation is a type of cellular reprogramming involving the conversion of one differentiated cell type to another. This remarkable phenomenon holds enormous promise for the field of regenerative medicine. Over the last 20 years techniques used to reprogram...
Biochem Soc Trans (2014) 42 (3): 609–616.
Published: 22 May 2014
... leading to the development of metaplasia is therefore of significant clinical interest. In contrast, transdifferentiation (or cellular reprogramming) is a subset of metaplasia that describes the permanent conversion of one differentiated cell type into another, and generally occurs between cells...
Biochem Soc Trans (2008) 36 (3): 280–285.
Published: 21 May 2008
... hormone GLP-1 (glucagon-like peptide 1). Finally, in vitro models demonstrate a central role for EGFR in transdifferentiation of pancreatic acinar and ductal cells into endocrine islet cells. EGFR thus plays an essential role in β-cell mass regulation, but its mechanisms of action remain poorly understood...
Biochem Soc Trans (2002) 30 (2): 51–54.
Published: 01 April 2002
...David Tosh; Chia-Ning Shen; Jonathan M. W. Slack Transdifferentiation is the name used to describe the conversion of one differentiated cell type to another. During development, the liver and pancreas arise from the same region of the endoderm and cells from the two organs can transdifferentiate...