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Keywords: transcriptional regulation
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Articles
Biochem Soc Trans (2017) 45 (4): 953–962.
Published: 07 July 2017
... inflammation lncRNA transcriptional regulation © 2017 The Author(s); published by Portland Press Limited on behalf of the Biochemical Society 2017 17 3 2017 26 5 2017 12 6 2017 Correspondence: Loretta Magagula ( loretta@mhlangalab.org ) or Musa Mhlanga ( musa@mhlangalab.org...
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Biochem Soc Trans (2015) 43 (4): 595–601.
Published: 03 August 2015
... expression and activity is essential. This regulation is exerted at multiple levels, including transcriptional regulation and proteasomal degradation. Recent studies revealed important roles of miRNAs (miRs) in the control of NRF2 activity through direct targeting of the NRF2 mRNA and of mRNAs encoding...
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Biochem Soc Trans (2013) 41 (6): 1634–1639.
Published: 20 November 2013
... of chromatin from one nuclear compartment to another, nuclear structures might not only be relevant as a reference point, but also indicate a biological function [ 2 , 3 ]. chromatin fission yeast heterochromatin nuclear organization transcriptional regulation For live-cell imaging purposes...
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Biochem Soc Trans (2011) 39 (1): 99–103.
Published: 19 January 2011
... The Authors Journal compilation © 2011 Biochemical Society 2011 activator archaeon transcriptional regulation transcription factor B-recognition element (BRE) transcription factor B recruitment (TFB recruitment) upstream activator sequence (UAS) The archaeal transcriptional machinery...
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Biochem Soc Trans (2008) 36 (6): 1252–1257.
Published: 19 November 2008
... christer.hogstrand@kcl.ac.uk ). 11 6 2008 © The Authors Journal compilation © 2008 Biochemical Society 2008 genomics metal-regulatory transcription factor 1 (MTF1) small interfering RNA (siRNA) transcriptional regulation zinc MTF1 (metal-regulatory transcription factor 1...
Includes: Supplementary data
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Biochem Soc Trans (2008) 36 (4): 609–612.
Published: 22 July 2008
... in transcriptional regulation. In the present paper, we shall review the literature demonstrating the action of p68 and, where data are available, p72 as transcriptional co-regulators for a range of transcription factors, namely ERα (oestrogen receptor α), the tumour suppressor p53, the myogenic regulator MyoD...
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Biochem Soc Trans (2008) 36 (4): 758–765.
Published: 22 July 2008
..., the challenge to understand how the individual genes are regulated within the cell remains. Here, I provide an overview of current computational methods to investigate transcriptional regulation. I will first discuss how representing protein–DNA interactions as a network provides us with a conceptual framework...
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Biochem Soc Trans (2008) 36 (4): 613–618.
Published: 22 July 2008
... and clinical settings. Transcriptional regulation, the ability to turn genes on and off, lies at the heart of these processes of lineage commitment and specification. We have focused on fully understanding how these decisions are made at a single mammalian gene locus, the α-globin genes, which become up...
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Biochem Soc Trans (2008) 36 (4): 599–602.
Published: 22 July 2008
... Biochemical Society 2008 chromatin switching ion channel oncogene transcriptional regulation tumour suppressor vascular disease Eukaryotic DNA is wrapped around histone proteins forming a complex known as chromatin. Although initially thought to solely serve a structural role, facilitating...
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Biochem Soc Trans (2008) 36 (1): 83–88.
Published: 22 January 2008
...-binding protein nucleotide analogue σ 54 transcriptional regulation bEBPs (bacterial enhancer-binding proteins) are AAA+ (ATPase associated with various cellular activities) family members involved in regulating bacterial gene expression. Regulated transcription in bacteria requires...
Articles
Biochem Soc Trans (2008) 36 (1): 89–93.
Published: 22 January 2008
...-angle X-ray scattering (SAXS/WAXS) transcriptional regulation © The Authors Journal compilation © 2008 Biochemical Society 2008 28 9 2007 1 To whom correspondence should be addressed (email btn1@psu.edu ). Bacteria must adapt to environmental changes quickly...
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Biochem Soc Trans (2007) 35 (6): 1427–1429.
Published: 23 November 2007
...F.V. Fuller-Pace; A.-M.F. Jacobs; S.M. Nicol SUMO (small ubiquitin-related modifier) modification is known to have diverse effects on the activity of transcriptional regulators, often through alterations in their localization or interactions with other factors, and in most of the cases...
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Biochem Soc Trans (2006) 34 (6): 1128–1131.
Published: 25 October 2006
... transcriptional regulation Altered macrophage functions contribute to the pathogenesis of many infectious, immunological and inflammatory disease processes. Pharmacological modulation of macrophage gene expression therefore represents an important strategy for the prevention and treatment of inflammation...
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Biochem Soc Trans (2006) 34 (1): 185–187.
Published: 20 January 2006
...S. Rinaldo; G. Giardina; M. Brunori; F. Cutruzzolà All denitrifiers can keep the steady-state concentrations of nitrite and nitric oxide (NO) below cytotoxic levels by controlling the expression of denitrification gene clusters by redox signalling through transcriptional regulators belonging...
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Biochem Soc Trans (2005) 33 (6): 1423–1426.
Published: 26 October 2005
... ). 21 6 2005 © 2005 The Biochemical Society 2005 chromatin immunoprecipitation–DNA microarray (ChIP-chip) gene circuit metabolism network component analysis (NCA) transcriptional regulation transcription factor There are many published works concerned with the deduction...
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Biochem Soc Trans (2005) 33 (6): 1537–1540.
Published: 26 October 2005
.... 1 To whom correspondence should be addressed (email a.bird@ed.ac.uk ). 20 6 2005 © 2005 The Biochemical Society 2005 DNA methylation epigenetic mechanism histone deacetylase methyl-CpG-binding domain protein transcriptional regulation tumorigenesis In addition...
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Biochem Soc Trans (2005) 33 (1): 195–197.
Published: 01 February 2005
... ]. 1 To whom correspondence should be addressed (email NXF122@bham.ac.uk ). 25 9 2004 © 2005 The Biochemical Society 2005 anaerobiosis hybrid-cluster protein iron–sulphur–oxygen cluster nitrogen cycle transcription start mapping transcriptional regulation The HCP...
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Biochem Soc Trans (2004) 32 (6): 1008–1010.
Published: 26 October 2004
... transcription factor. 1 To whom correspondence should be addressed (email chb@soton.ac.uk ). 22 7 2004 © 2004 The Biochemical Society 2004 Nramp1 oxidant stress specificity protein 1 (Sp1) transcriptional regulation Nramp1 (murine natural resistance-associated...
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