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Keywords: trans-signalling
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Articles
Biochem Soc Trans (2018) 46 (6): 1449–1462.
Published: 22 November 2018
...Mustafa Yassin Taher; David Marc Davies; John Maher Interleukin-6 (IL-6) is a pleiotropic cytokine that activates a classic signalling pathway upon binding to its membrane-bound receptor (IL-6R). Alternatively, IL-6 may ‘trans-signal’ in a manner that is facilitated by its binding to a soluble...