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Keywords: torsinA
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Biochem Soc Trans (2011) 39 (6): 1719–1724.
Published: 21 November 2011
... intermediate filament nesprin-3 plakin plectin SUN protein torsinA In eukaryotic cells, the nucleus is surrounded by an NE (nuclear envelope), consisting of an inner and an outer nuclear membrane [ 1 ]. The nucleus is mechanically coupled to the cytoskeleton by members of the nesprin protein...
Biochem Soc Trans (2010) 38 (2): 452–456.
Published: 22 March 2010
... in the C-terminus of the protein TA (torsinA). TA is a member of the AAA+ (ATPase associated with various cellular activities) family of chaperones with multiple functions in the cell. There is no evidence of neurodegeneration in DYT1 dystonia, which suggests that mutant TA leads to functional neuronal...