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Keywords: telomeres
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Biochem Soc Trans (2021) 49 (5): 1927–1939.
Published: 08 October 2021
...Thi Hoang Duong Nguyen Telomerase ribonucleoprotein was discovered over three decades ago as a specialized reverse transcriptase that adds telomeric repeats to the ends of linear eukaryotic chromosomes. Telomerase plays key roles in maintaining genome stability; and its dysfunction...
Biochem Soc Trans (2021) 49 (2): 933–943.
Published: 26 March 2021
... is not elicited at chromosome ends, which are organized in nucleoprotein structures called telomeres. Besides counteracting DSB response through specialized telomere-binding proteins, telomeres also prevent chromosome shortening. Despite of the different fate of telomeres and DSBs, many proteins involved...