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Keywords: syndecan
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Biochem Soc Trans (2018) 46 (2): 371–377.
Published: 09 March 2018
...Rafael S. Aquino; Yvonne Hui-Fang Teng; Pyong Woo Park Syndecan-1 (Sdc1) is a major cell surface heparan sulfate (HS) proteoglycan of epithelial cells, a cell type targeted by many bacterial pathogens early in their pathogenesis. Loss of Sdc1 in mice is a gain-of-function mutation...
Biochem Soc Trans (2015) 43 (1): 122–128.
Published: 26 January 2015
... identified integrin trafficking, syndecan signalling and adhesion receptor–growth factor receptor cross-talk mechanisms might dynamically control the function, assembly and mechanical properties of a viable, and mechanoresponsive, fibronectin network. The biochemical and biophysical properties...
Biochem Soc Trans (2014) 42 (6): 1643–1646.
Published: 17 November 2014
...Giulia De Rossi; James R. Whiteford Syndecans are multifunctional heparan sulfate proteoglycans (HSPGs) with roles in cell adhesion, migration, receptor trafficking and growth-factor interactions and signalling. Studies using syndecan null animals have revealed limited roles for syndecans during...
Biochem Soc Trans (2007) 35 (4): 788–793.
Published: 20 July 2007
... as mutually exclusive, as more than one entry mechanism may be operational for a given cationic complex in a particular cell type. Specifically, the observed import may best be explained by the distribution and uptake of cell-surface HSPGs (heparan sulfate proteoglycans), such as syndecans and glypicans...
Biochem Soc Trans (2006) 34 (3): 418–421.
Published: 22 May 2006
... that they have additional important functions, for instance in the vasculature and immune system. Genetic studies have identified two types of cellular receptors for Slits: Robos (Roundabout) and the HS (heparan sulphate) proteoglycan syndecan. The intracellular signalling cascade downstream of Robo activation...