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Keywords: substrate preference
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Biochem Soc Trans (2006) 34 (6): 1161–1164.
Published: 25 October 2006
... is found in vivo in procyclic forms of TB and is a good TB CYP51 substrate in vitro . We believe that (i) N is a non-conventional CYP51 substrate, preferred in TB and perhaps other Trypanosomatidae and (ii) functional similarity of TC CYP51 to animal/fungal orthologues is a result of evolutionary...