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Keywords: structure-guided drug discovery
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Biochem Soc Trans (2017) 45 (2): 303–311.
Published: 13 April 2017
... analysis structure-guided drug discovery Ideas about the use of protein structure in drug discovery emerged in parallel with the first three-dimensional structures defined by X-ray crystallography. An early focus on the structure of haemoglobin in the 1950s stimulated thoughts about sickle cell...