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Biochem Soc Trans (2017) 45 (1): 229–236.
Published: 15 February 2017
...Begum Erdogan; Donna J. Webb Cancer-associated fibroblasts (CAFs) are major components of the surrounding stroma of carcinomas that emerge in the tumor microenvironment as a result of signals derived from the cancer cells. Biochemical cross-talk between cancer cells and CAFs as well as mechanical...
Biochem Soc Trans (2010) 38 (3): 783–788.
Published: 24 May 2010
... membrane protein with an N-terminal domain extending into the stroma. Interestingly, despite the relatively recent evolution and high similarity of ARC6 and PARC6, PARC6 has evolved to have strikingly adverse functions from ARC6; whereas ARC6 is thought to stabilize the Z-ring, PARC6 appears to destabilize...
Biochem Soc Trans (2010) 38 (2): 327–330.
Published: 22 March 2010
...-environment can influence epithelial cell behaviour across a number of disease sites, and Barrett's oesophagus is another example. More research is required to understand the key cell components in the stroma which influence cancer development. Ultimately, such knowledge should enable optimal strategies...