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Keywords: small ubiquitin-related modifier (SUMO)
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Articles
Biochem Soc Trans (2010) 38 (1): 60–64.
Published: 19 January 2010
... The Authors Journal compilation © 2010 Biochemical Society 2010 Arabidopsis conjugation machinery plant protein target small ubiquitin-related modifier (SUMO) The covalent attachment of SUMO (small ubiquitin-related modifier) to target proteins constitutes a mechanism of protein regulation...
Articles
Biochem Soc Trans (2010) 38 (1): 34–39.
Published: 19 January 2010
... small ubiquitin-related modifier (SUMO) synergistic outcome ubiquitin-like molecule Post-translational modifications are one of the most effective ways by which evolution has increased the versatility in protein function using a relative paucity of genes. These covalent modifications...
Articles
Biochem Soc Trans (2010) 38 (1): 92–97.
Published: 19 January 2010
...) protein inhibitor of activated STAT (PIAS) small ubiquitin-related modifier (SUMO) DNA lesions can occur through exogenous and endogenous damage. Damage triggers activation of DNA repair or damage-avoidance pathways: a checkpoint response followed by cell-cycle arrest to allow time for the repair...
Articles
Biochem Soc Trans (2010) 38 (1): 116–131.
Published: 19 January 2010
... modifications and interactions that regulate nucleotide excision repair, translesion synthesis, double-strand break repair and interstrand cross-link repair, with the discussion of relevant examples in each pathway. DNA damage DNA repair phosphorylation small ubiquitin-related modifier (SUMO) ubiquitin...
Articles
Biochem Soc Trans (2010) 38 (1): 54–59.
Published: 19 January 2010
...). Mutations in the above-mentioned proteins cause congenital adrenal hyperplasia, one of the most common inherited metabolic disorders, which includes adrenal insufficiency, genital ambiguity and effects on sexual characteristics. adrenal cortex small ubiquitin-related modifier (SUMO...
Articles
Biochem Soc Trans (2010) 38 (1): 46–49.
Published: 19 January 2010
...-associated protein E (CENP-E) small ubiquitin-related modifier (SUMO) Ubc9 ubiquitin-like protease 2 (Ulp2) SUMOs (small ubiquitin-related modifiers) regulate the activity of target proteins via covalent modification [ 1 ]. SUMOylation can alter the function of target proteins by regulating...
Articles
Biochem Soc Trans (2008) 36 (5): 874–878.
Published: 19 September 2008
... should be addressed (email guillaume.bossis@igmm.cnrs.fr ). 4 3 2008 © The Authors Journal compilation © 2008 Biochemical Society 2008 conjugation phospho-dependent SUMO motif (PDSM) phosphorylation post-translational modification small ubiquitin-related modifier (SUMO) stress...
Articles
Biochem Soc Trans (2008) 36 (5): 828–832.
Published: 19 September 2008
... Society 2008 deISGylase deNEDDylase deSUMOylase deubiquitinating enzyme (DUB) high-throughput screening (HTS) isopeptidase small ubiquitin-related modifier (SUMO) The conjugation of Ub (ubiquitin) and UBLs (Ub-like proteins) is an important regulatory mechanism that is widespread...
Articles
Biochem Soc Trans (2008) 36 (3): 445–448.
Published: 21 May 2008
...@ucd.ie ). 11 1 2008 © The Authors Journal compilation © 2008 Biochemical Society 2008 cellular metabolism hypoxia metabolic stress post-translational modification small ubiquitin-related modifier (SUMO) SUMOylation Recent developments, which have facilitated genomic...
Articles
Articles
Biochem Soc Trans (2007) 35 (6): 1430–1432.
Published: 23 November 2007
... 21 6 2007 © The Authors Journal compilation © 2007 Biochemical Society 2007 E2 conjugating enzyme protein modification signal transducer and activator of transcription 1 (STAT1) small ubiquitin-related modifier (SUMO) SUMOylation-regulated phosphorylation Ubc9 fusion-directed...
Articles
Biochem Soc Trans (2007) 35 (6): 1409–1413.
Published: 23 November 2007
... motif (PDSM) small ubiquitin-related modifier (SUMO) transcription ubiquitin-conjugating enzyme 9 (Ubc9) Regulation of Protein Function by SUMO Modification: A Biochemical Society Focussed Meeting held at Manchester Conference Centre, Manchester, U.K., 25–27 June 2007. Organized and Edited...
Articles
Biochem Soc Trans (2007) 35 (6): 1385–1388.
Published: 23 November 2007
... The Authors Journal compilation © 2007 Biochemical Society 2007 genome stability DNA replication proliferating-cell nuclear antigen (PCNA) small ubiquitin-related modifier (SUMO) Srs2 yeast E1 ubiquitin- or SUMO-activating enzyme E2 ubiquitin- or SUMO-conjugating enzyme E3...
Articles
Biochem Soc Trans (2007) 35 (6): 1433–1435.
Published: 23 November 2007
... E2 protein human papillomavirus (HPV) keratinocyte differentiation small ubiquitin-related modifier (SUMO) SUMOylation viral protein Regulation of Protein Function by SUMO Modification: A Biochemical Society Focussed Meeting held at Manchester Conference Centre, Manchester, U.K., 25–27...
Articles
Biochem Soc Trans (2007) 35 (6): 1424–1426.
Published: 23 November 2007
...) pharyngeal muscle small ubiquitin-related modifier (SUMO) T-box protein 2 (TBX-2) ubiquitin-conjugating enzyme 9 (Ubc9) T-box transcription factors play essential roles in the development of all multicellular organisms, where their functions include cell fate specification and roles...
Articles
Biochem Soc Trans (2007) 35 (6): 1419–1421.
Published: 23 November 2007
... system. 1 email susanna.chiocca@ifom-ieo-campus.it 9 7 2007 © The Authors Journal compilation © 2007 Biochemical Society 2007 E1 activating enzyme elongin (Elo) Gam1 small ubiquitin-related modifier (SUMO) SUMOylation viral protein I thank all past and present...
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Biochem Soc Trans (2007) 35 (6): 1389–1392.
Published: 23 November 2007
.... Fujita N. Nakao M. J. Biol. Chem. 2005 280 13928 13935 © The Authors Journal compilation © 2007 Biochemical Society 2007 histone deacetylase (HDAC) protein–protein interaction small ubiquitin-related modifier (SUMO) transcriptional activation transcriptional repression...
Articles
Biochem Soc Trans (2007) 35 (6): 1414–1418.
Published: 23 November 2007
... (PDSM) small ubiquitin-related modifier (SUMO) SUMOylation Figure 1 The SUMO pathway and points of regulation Components of the SUMO pathway are shown as ovals, and a putative substrate as a rectangle. Only one E1 (SAE1/SAE2) and one E2 (Ubc9) enzyme exist but there are multiple potential...
Articles
Biochem Soc Trans (2007) 35 (6): 1393–1396.
Published: 23 November 2007
... with recruitment of HDAC activity and increased transcriptional repression. co-repressor histone deacetylase (HDAC) non-covalent interaction repression small ubiquitin-related modifier (SUMO) specificity protein 3 (Sp3) Sp3 belongs to the Sp (specificity protein) family of transcription factors...
Articles
Biochem Soc Trans (2007) 35 (6): 1422–1423.
Published: 23 November 2007
... is known about the identity of the endogenous target proteins that are conjugated to SUMO polymers. 1 email vertegaal@lumc.nl 22 6 2007 © The Authors Journal compilation © 2007 Biochemical Society 2007 chain formation E3 ligase polymer small ubiquitin-related modifier (SUMO...
Articles
Biochem Soc Trans (2006) 34 (6): 1295–1298.
Published: 25 October 2006
... SUMO conjugation status changes during the metabolic rate suppression of ground squirrel hibernation torpor. Akt cytoprotection hibernation ischaemia oligaemia small ubiquitin-related modifier (SUMO) We found on Western blotting that there is a marked elevation of protein SUMOylation...