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Keywords: small GTPase
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Articles
Biochem Soc Trans (2018) 46 (6): 1713–1720.
Published: 04 December 2018
...Amy L. Stiegler; Titus J. Boggon Pseudoenzymes generally lack detectable catalytic activity despite adopting the overall protein fold of their catalytically competent counterparts, indeed ‘pseudo’ family members seem to be incorporated in all enzyme classes. The small GTPase enzymes are important...
Articles
Biochem Soc Trans (2018) 46 (3): 649–658.
Published: 09 May 2018
... involved in the complex signalling processes that underpin the inflammatory response and cross-talk between endothelium and leukocytes. As key regulators of cell–cell and cell–substratum adhesion, small GTPases (guanosine triphosphatases) act as important controls of neutrophil-endothelial cell...
Articles
Biochem Soc Trans (2015) 43 (1): 108–110.
Published: 26 January 2015
... to each other and it is thought that they maintain contact sites to exchange molecules. The regulation and the function of these contact sites need to be further explored. The small GTPase Arf1 (ADP-ribosylation factor 1), which is best known for its essential role in the generation of coatomer protein I...
Articles
Biochem Soc Trans (2010) 38 (2): 723–728.
Published: 22 March 2010
...Viktor Žárský; Martin Potocký The Rho/Rop small GTPase regulatory module is central for initiating exocytotically ACDs (active cortical domains) in plant cell cortex, and a growing array of Rop regulators and effectors are being discovered in plants. Structural membrane phospholipids are important...
Articles
Biochem Soc Trans (2006) 34 (5): 846–850.
Published: 25 October 2006
... of this family are GAP1 m , GAP1 IP4BP , CAPRI (Ca 2+ -promoted Ras inactivator) and RASAL (Ras-GTPase-activating-like protein) and, as we will discuss, they are emerging as important modulators of Ras and small GTPase signalling that are subject to regulation by a diverse array of events and second messenger...