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Keywords: skeletal muscle
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Articles
Biochem Soc Trans (2021) 49 (1): 477–484.
Published: 15 January 2021
... and survival through its αV/β5 integrin receptor. Correspondence: Maria Grano ( maria.grano@uniba.it ) 1 10 2020 8 12 2020 14 12 2020 © 2021 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2021 bone Irisin skeletal muscle...
Articles
Biochem Soc Trans (2018) 46 (1): 111–118.
Published: 12 January 2018
...Francis B. Stephens; Kostas Tsintzas The molecular and metabolic mechanisms underlying the increase in insulin sensitivity (i.e. increased insulin-stimulated skeletal muscle glucose uptake, phosphorylation and storage as glycogen) observed from 12 to 48 h following a single bout of exercise...
Articles
Biochem Soc Trans (2014) 42 (6): 1550–1555.
Published: 17 November 2014
... activation and suggest that inhibition of PKCθ could represent a novel therapeutic approach in the treatment of chronic inflammation, autoimmunity and allograft rejection. However, considering that PKCθ is also expressed in other cell types, including skeletal muscle cells, it is important to understand its...
Articles
Biochem Soc Trans (2014) 42 (6): 1616–1622.
Published: 17 November 2014
...Ylva Hellsten; Birgitte Hoier In human skeletal muscle, the capillary net readily adapts according to the level of muscular activity to allow for optimal diffusion conditions for oxygen from the blood to the muscle. Animal studies have demonstrated that stimulation of capillary growth in skeletal...
Articles
Biochem Soc Trans (2014) 42 (4): 965–970.
Published: 11 August 2014
...Brian McDonagh; Giorgos K. Sakellariou; Malcolm J. Jackson Skeletal muscle represents a physiologically relevant model for the application of redox proteomic techniques to dissect its response to exercise and aging. Contracting skeletal muscles generate ROS (reactive oxygen species) and RNS...
Articles
Biochem Soc Trans (2011) 39 (6): 1628–1632.
Published: 21 November 2011
...Thomas Gustafsson Exercise-induced angiogenesis in skeletal muscle involves both non-sprouting and sprouting angiogenesis and results from the integrated responses of multiple systems and stimuli. VEGF-A (vascular endothelial growth factor A) levels are increased in exercised muscle and have been...
Articles
Biochem Soc Trans (2011) 39 (6): 1633–1638.
Published: 21 November 2011
... (vascular endothelial growth factor) flow-dependent nitric oxide release in remodelling skeletal muscle microcirculation is established for elevated (activity, dilatation) and reduced (overload, ischaemia) shear stress, although their temporal relationship to angiogenesis varies. It is clear that growth...
Articles
Biochem Soc Trans (2010) 38 (5): 1294–1301.
Published: 24 September 2010
... moderately successful. In the present review, we compare kinetic models of glycolysis in three cell types (African trypanosomes, yeast and skeletal muscle), evaluate their predictive power and identify limitations in our understanding. Although each of these models has its own merits and shortcomings...
Articles
Biochem Soc Trans (2007) 35 (5): 1310–1311.
Published: 25 October 2007
... have examined the effects of exercise on basal and insulin-mediated changes in the activation (phosphorylation) of the signalling molecules involved in the regulation of SREBP-1c and related them to changes in the expression of SREBP-1c in human skeletal muscle. Eight healthy men performed one-legged...
Articles
Biochem Soc Trans (2007) 35 (5): 1295–1297.
Published: 25 October 2007
... compilation © 2007 Biochemical Society 2007 adipose tissue cytokine diabetes insulin resistance interleukin skeletal muscle Over the past decade, there has been an increasing focus on the role of inflammation in the pathogenesis of several chronic diseases. Low-grade chronic inflammation...
Articles
Biochem Soc Trans (2005) 33 (6): 1513–1517.
Published: 26 October 2005
...F.S. Walsh; A.J. Celeste Myostatin, or GDF-8 (growth and differentiation factor-8), was first identified through sequence identity with members of the BMP (bone morphogenetic protein)/TGF-β (transforming growth factor-β) superfamily. The skeletal-muscle-specific expression pattern of myostatin...
Articles
Biochem Soc Trans (2005) 33 (2): 354–357.
Published: 01 April 2005
...M. Björnholm; J.R. Zierath Type II diabetes is characterized by defects in insulin action on peripheral tissues, such as skeletal muscle, adipose tissue and liver and pancreatic β-cell defects. Since the skeletal muscle accounts for approx. 75% of whole body insulin-stimulated glucose uptake...
Articles
Biochem Soc Trans (2003) 31 (6): 1290–1294.
Published: 01 December 2003
.... In this mini-review focus is on AMPK and its regulatory role for glucose transport and GS (glycogen synthase) activity in skeletal muscle, indicating that AMPK is a GS kinase in vivo which might influence GS activity during exercise and that AMPK is involved in AICAR/hypoxia-induced glucose transport...
Articles
Biochem Soc Trans (2003) 31 (2): 455–456.
Published: 01 April 2003
...A. Vasilaki; L.M Iwanejko; F. McArdle; C.S. Broome; M.J. Jackson; A. McArdle Skeletal muscle adapts rapidly following exercise by the increased production of heat-shock proteins (HSPs). The aim of this study was to examine the ability of muscle from adult and aged mice to produce HSPs following non...
Articles
Biochem Soc Trans (2003) 31 (1): 186–190.
Published: 01 February 2003
...J.N. Nielsen; S.B. Jørgensen; C. Frøsig; B. Viollet; F. Andreelli; S. Vaulont; B. Kiens; E.A. Richter; J.F.P. Wojtaszewski Exercise-induced glucose uptake in skeletal muscle is mediated by an insulin-independent mechanism, but the actual signals to glucose transport in response to muscle...
Articles
Biochem Soc Trans (2002) 30 (2): 275–280.
Published: 01 April 2002
... dehydrogenase complex o 2 max, maximal oxygen consumption acetylcamitine acetyl-CoA pyruvate dehydrogenase complex skeletal muscle Skeletal Muscle Energetics and Exercise Tolerance I I I 2 13 14 15 16 17 18 19 Pond, C. M. and Mattacks, C. A. (2002) Cytokine, MacQueen, H. A. and Pond, C. M...