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Keywords: signalling scaffold
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Journal:
Biochemical Society Transactions
Biochem Soc Trans (2019) 47 (1): 197–207.
Published: 21 December 2018
... displays intrinsic GTPase activity and functions as a signalling scaffold. As an example, LRRK2 was suggested to be part of the NRON complex and β-catenin destruction complex, inhibiting NFAT and canonical Wnt signalling, respectively. In summary, continuous research into LRRK2 signalling function...
