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Keywords: signal transducer and activator of transcription (STAT)
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Articles
Biochem Soc Trans (2014) 42 (1): 59–62.
Published: 23 January 2014
... (ERK) inflammation interleukin 6-type cytokine Janus kinase (JAK) signal transducer and activator of transcription (STAT) IL (interleukin)-6-type cytokines are critical molecules that determine health and disease in many living organisms (reviewed in [ 1 , 2 ]). The IL-6 family of cytokines...
Articles
Biochem Soc Trans (2013) 41 (4): 1042–1047.
Published: 18 July 2013
... (email babon@wehi.edu.au ). 3 5 2013 © The Authors Journal compilation © 2013 Biochemical Society 2013 cytokine signalling Janus kinase (JAK) signal transducer and activator of transcription (STAT) suppressor of cytokine signalling (SOCS) Cytokines signal by binding...
Articles
Biochem Soc Trans (2012) 40 (1): 215–218.
Published: 19 January 2012
... cytokine exchange protein directly activated by cAMP (Epac) Janus kinase (JAK) signal transducer and activator of transcription (STAT) suppressor of cytokine signalling (SOCS) ubiquitin ligase Cytokines control many important biological responses, including haemopoiesis, inflammation and T...
Articles
Biochem Soc Trans (2010) 38 (1): 92–97.
Published: 19 January 2010
... an important role in the yeast response to replicative stress [ 2 , 3 ]. 15 10 2009 © The Authors Journal compilation © 2010 Biochemical Society 2010 breast-cancer susceptibility gene 1 (BRCA1) DNA damage double-stranded DNA signal transducer and activator of transcription (STAT...
Articles
Biochem Soc Trans (2008) 36 (6): 1448–1451.
Published: 19 November 2008
... cytokine receptors as the technique allows modification of the bait protein in a physiologically optimal environment. cytokine receptor mammalian protein–protein interaction trap (MAPPIT) signal transducer and activator of transcription (STAT) signal transduction suppressor of cytokine signalling...
Articles
Biochem Soc Trans (2008) 36 (3): 328–333.
Published: 21 May 2008
... destruction in Type 1 diabetes [ 51 ]. β-cell cytokine diabetes interferon γ (IFNγ) Janus kinase (JAK) signal transducer and activator of transcription (STAT) Type 1 diabetes results from an autoimmune destruction of the insulin-producing β-cells of the islets of Langerhans...
Articles
Biochem Soc Trans (2008) 36 (2): 235–239.
Published: 20 March 2008
... integrin signal transducer and activator of transcription (STAT) talin vinculin α-Actinin is a rod-shaped antiparallel dimer of two 100 kDa monomers; this configuration positions its actin-binding CH (calponin homology domain) motifs at either end of the rod domain, an arrangement that allows α...
Articles
Biochem Soc Trans (2007) 35 (6): 1405–1408.
Published: 23 November 2007
... STAT (PIAS) really interesting new gene (RING) domain signal transducer and activator of transcription (STAT) small ubiquitin-related modifier (SUMO) transcription co-regulator PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] proteins were...
Articles
Biochem Soc Trans (2005) 33 (5): 1126–1128.
Published: 26 October 2005
... ). 26 7 2005 © 2005 The Biochemical Society 2005 cAMP cytokine receptor endothelial cell (EC) interleukin-6 phosphorylation signal transducer and activator of transcription (STAT) This work is supported by the British Heart Foundation, Heart Research U.K. and the Biotechnology...