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Keywords: signal transducer and activator of transcription (STAT)
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Articles
Biochem Soc Trans (2014) 42 (1): 59–62.
Published: 23 January 2014
... 5 12 2013 © The Authors Journal compilation © 2014 Biochemical Society 2014 cancer extracellular-signal-regulated kinase (ERK) inflammation interleukin 6-type cytokine Janus kinase (JAK) signal transducer and activator of transcription (STAT) IL (interleukin)-6-type...
Articles
Biochem Soc Trans (2013) 41 (4): 1042–1047.
Published: 18 July 2013
... Society 2013 cytokine signalling Janus kinase (JAK) signal transducer and activator of transcription (STAT) suppressor of cytokine signalling (SOCS) Cytokines signal by binding to specific cell-surface receptors on their target cell. The cytoplasmic domains of these cytokine receptors...
Articles
Biochem Soc Trans (2012) 40 (1): 215–218.
Published: 19 January 2012
... cytokine exchange protein directly activated by cAMP (Epac) Janus kinase (JAK) signal transducer and activator of transcription (STAT) suppressor of cytokine signalling (SOCS) ubiquitin ligase Cytokines control many important biological responses, including haemopoiesis, inflammation and T...
Articles
Biochem Soc Trans (2010) 38 (1): 92–97.
Published: 19 January 2010
... after DNA damage. The present review examines roles described for the SUMO pathway in the way mammalian cells respond to genotoxic stress. breast-cancer susceptibility gene 1 (BRCA1) DNA damage double-stranded DNA signal transducer and activator of transcription (STAT) protein inhibitor...
Articles
Biochem Soc Trans (2008) 36 (6): 1448–1451.
Published: 19 November 2008
... receptor mammalian protein–protein interaction trap (MAPPIT) signal transducer and activator of transcription (STAT) signal transduction suppressor of cytokine signalling (SOCS) Toll-like receptor (TLR) Cytokines are small messenger molecules that are involved in cell–cell communication...
Articles
Biochem Soc Trans (2008) 36 (3): 328–333.
Published: 21 May 2008
... The Authors Journal compilation © 2008 Biochemical Society 2008 β-cell cytokine diabetes interferon γ (IFNγ) Janus kinase (JAK) signal transducer and activator of transcription (STAT) Type 1 diabetes results from an autoimmune destruction of the insulin-producing β-cells of the islets...
Articles
Biochem Soc Trans (2008) 36 (2): 235–239.
Published: 20 March 2008
...@nottingham.ac.uk ). 11 1 2008 © The Authors Journal compilation © 2008 Biochemical Society 2008 α-actinin focal adhesion integrin signal transducer and activator of transcription (STAT) talin vinculin Cell adhesion contributes to most common human diseases including inflammation...
Articles
Biochem Soc Trans (2007) 35 (6): 1405–1408.
Published: 23 November 2007
... STAT (PIAS) really interesting new gene (RING) domain signal transducer and activator of transcription (STAT) small ubiquitin-related modifier (SUMO) transcription co-regulator PIAS proteins harbour a region rich in cysteine residues that may form a RING finger type of motif termed Siz/PIAS...
Articles
Biochem Soc Trans (2005) 33 (5): 1126–1128.
Published: 26 October 2005
... and activator of transcription (STAT) Under normal physiological conditions, the endothelium acts as a multifunctional anti-coagulant, anti-inflammatory and anti-thrombotic barrier [ 1 ]. However, the ability of vascular ECs (endothelial cells) to dramatically alter their phenotype to evoke a pro...