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1-9 of 9
Keywords: signal transducer and activator of transcription (STAT)
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Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2014) 42 (1): 59–62.
Published: 23 January 2014
... (ERK) inflammation interleukin 6-type cytokine Janus kinase (JAK) signal transducer and activator of transcription (STAT) IL (interleukin)-6-type cytokines are critical molecules that determine health and disease in many living organisms (reviewed in [ 1 , 2 ]). The IL-6 family of cytokines...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2013) 41 (4): 1042–1047.
Published: 18 July 2013
... Society 2013 cytokine signalling Janus kinase (JAK) signal transducer and activator of transcription (STAT) suppressor of cytokine signalling (SOCS) Cytokines signal by binding to specific cell-surface receptors on their target cell. The cytoplasmic domains of these cytokine receptors...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2012) 40 (1): 215–218.
Published: 19 January 2012
... cytokine exchange protein directly activated by cAMP (Epac) Janus kinase (JAK) signal transducer and activator of transcription (STAT) suppressor of cytokine signalling (SOCS) ubiquitin ligase Cytokines control many important biological responses, including haemopoiesis, inflammation and T...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2010) 38 (1): 92–97.
Published: 19 January 2010
...-stranded DNA signal transducer and activator of transcription (STAT) protein inhibitor of activated STAT (PIAS) small ubiquitin-related modifier (SUMO) DNA lesions can occur through exogenous and endogenous damage. Damage triggers activation of DNA repair or damage-avoidance pathways...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2008) 36 (6): 1448–1451.
Published: 19 November 2008
... receptor mammalian protein–protein interaction trap (MAPPIT) signal transducer and activator of transcription (STAT) signal transduction suppressor of cytokine signalling (SOCS) Toll-like receptor (TLR) Cytokines are small messenger molecules that are involved in cell–cell communication...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2008) 36 (3): 328–333.
Published: 21 May 2008
... in their gene/protein expression, rendering them more susceptible to the deadly effects of cytokines and poly(I:C). β-cell cytokine diabetes interferon γ (IFNγ) Janus kinase (JAK) signal transducer and activator of transcription (STAT) IL-1β and TNFα exert their effects in β-cells mainly through...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2008) 36 (2): 235–239.
Published: 20 March 2008
... shown to be highly temperature-dependent with no interactions observed at lower temperatures and then stronger binding seen at closer to physiological 37 °C [ 10 ]. α-actinin focal adhesion integrin signal transducer and activator of transcription (STAT) talin vinculin To advance...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2007) 35 (6): 1405–1408.
Published: 23 November 2007
... STAT (PIAS) really interesting new gene (RING) domain signal transducer and activator of transcription (STAT) small ubiquitin-related modifier (SUMO) transcription co-regulator AR androgen receptor ARIP3 AR-interacting protein 3 Elk-1 ETS (E twenty-six)-like kinase 1 GR...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2005) 33 (5): 1126–1128.
Published: 26 October 2005
... The Biochemical Society 2005 cAMP cytokine receptor endothelial cell (EC) interleukin-6 phosphorylation signal transducer and activator of transcription (STAT) Under normal physiological conditions, the endothelium acts as a multifunctional anti-coagulant, anti-inflammatory and anti-thrombotic...