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Keywords: scaffold protein
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Biochem Soc Trans (2007) 35 (5): 1278–1282.
Published: 25 October 2007
... to reveal the molecular mechanisms by which synaptic vesicles, ion channels, receptors and other synaptic components assemble to make a functional synapse. Recent evidence has shown that the formation and function of synapses are critically regulated by the liprin-α family of scaffolding proteins...
Biochem Soc Trans (2006) 34 (5): 828–832.
Published: 25 October 2006
...A.J. Whitmarsh The components of MAPK (mitogen-activated protein kinase) signalling pathways can assemble into complexes that are co-ordinated by regulatory proteins including scaffold proteins. There is increasing evidence that scaffold proteins (i) maintain signalling specificity and facilitate...
Biochem Soc Trans (2006) 34 (5): 837–841.
Published: 25 October 2006
... several mechanisms that can promote specificity in MAPK signalling, including tethering interactions between MAPKs and their substrates and regulators mediated by docking sites, feedback loops and cross-pathway regulatory circuits, and the selective activation of scaffold proteins. Genetics studies...