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Keywords: riboswitch
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Biochem Soc Trans (2019) 47 (5): 1279–1289.
Published: 23 October 2019
... expression and regulation riboswitch small non-coding RNA synthetic biology Synthetic biology combines biological sciences with the principles of engineering. This field has grown exponentially and promises to revolutionize biotechnology and medicine [ 1 ]. It is a scientific field that seeks...
Biochem Soc Trans (2011) 39 (2): 647–651.
Published: 22 March 2011
...Kathryn D. Smith; Scott A. Strobel The c-di-GMP [bis-(3′–5′)-cyclic dimeric guanosine monophosphate] riboswitch is a macromolecular target in the c-di-GMP second messenger signalling pathway. It regulates many genes related to c-di-GMP metabolism as well as genes involved in bacterial motility...
Biochem Soc Trans (2011) 39 (2): 652–657.
Published: 22 March 2011
...Elena Cressina; Liuhong Chen; Michael Moulin; Finian J. Leeper; Chris Abell; Alison G. Smith Riboswitches are regions of mRNA to which a metabolite binds in the absence of proteins, resoulting in alteration of transcription, translation or splicing. The most widespread forms of riboswitches...
Biochem Soc Trans (2006) 34 (2): 330–333.
Published: 20 March 2006
..., on a completely different tack, SAM can bind to certain RNA structures called riboswitches that control transcription or translation. In this way, expression of multiple genes can be regulated in a SAM-dependent manner, an unexpected finding that opens up new avenues into gene control. This minireview discusses...
Biochem Soc Trans (2005) 33 (3): 474–476.
Published: 01 June 2005
...B. Suess We have developed conditional gene expression systems based on engineered small-molecule-binding riboswitches. Tetracycline-dependent regulation can be imposed on an mRNA in yeast by inserting an aptamer in its 5′-untranslated region. Biochemical and genetic analyses determined...