...David Shore; Sevil Zencir; Benjamin Albert Ribosome biogenesis requires prodigious transcriptional output in rapidly growing yeast cells and is highly regulated in response to both growth and stress signals. This minireview focuses on recent developments in our understanding of this regulatory...

... grey filling. The species with YbeY homologues described in literature are shown. SAR — Stramenopiles-Alveolata-Rhizaria group, CPR — Candidate Phyla Radiation. Phylogenetic groups are given according to [ 109 , 110 ]. Era ribosome biogenesis uS11 YbeY Some proteins evolve fast...

... in proteins involved in the global process of ribosome biogenesis, result in tissue-specific defects. The questions posed by this dichotomy and the steps taken to address these questions are therefore the focus of this review: How can tissue-specific disorders result from alterations in global processes...

...Tina McLeod; Akilu Abdullahi; Min Li; Saverio Brogna The nucleolus is the most prominent morphological feature within the nucleus of eukaryotic cells and is best known for its role in ribosome biogenesis. It forms around highly transcribed ribosomal RNA gene repeats which yield precursor rRNAs...

... ]), although additional mechanisms may also be involved. mTORC1 activates Pol III by alleviating its inhibition by Maf1 [ 17 , 18 ]. mTORC1 co-localizes with Maf1 and promotes its phosphorylation. Given the complexity of ribosome biogenesis, with the necessity to generate sufficient quantities of almost 80...

... in ribosome biogenesis. 1 To whom correspondence should be addressed (email C.G.Proud@soton.ac.uk ). 4 8 2011 © The Authors Journal compilation © 2012 Biochemical Society 2012 mammalian target of rapamycin (mTOR) mRNA protein synthesis rapamycin ribosome biogenesis translation...

... compilation © 2011 Biochemical Society 2011 bioprocess control recombinant membrane protein production ribosome biogenesis stress yeast Membrane proteins are central to many cellular processes: they are involved in the uptake and export of diverse charged and uncharged molecules, as well...