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Keywords: rheumatoid arthritis
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Biochem Soc Trans (2014) 42 (6): 1752–1755.
Published: 17 November 2014
... the pharmacokinetics and pharmacodynamics are dissociated. The three murine models to be discussed each show BiP induced long-term therapeutic protection and therefore has potential for long-lasting drug-free therapy in rheumatoid arthritis (RA). © The Authors Journal compilation © 2014 Biochemical Society 2014...
Biochem Soc Trans (2014) 42 (4): 922–927.
Published: 11 August 2014
... that there was a significant, but weak, relationship with age. Interestingly, patients with rheumatoid arthritis and cancer have been described by others to secrete or express greater surface Trx-1 than predicted. It is interesting to speculate whether a decline in Trx-1 during ageing protects against such conditions...
Biochem Soc Trans (2014) 42 (2): 538–542.
Published: 20 March 2014
...Usman Ahmed; Paul J. Thornalley; Naila Rabbani OA (osteoarthritis) and RA (rheumatoid arthritis) lead to deterioration of the joints. Early OA is associated with loss of bone due to increased bone remodelling. A role for inflammation is thought to be integral to the pathology. RA is a chronic...
Biochem Soc Trans (2011) 39 (1): 327–330.
Published: 19 January 2011
... rheumatoid arthritis schizophrenia Glycosylation is one of the most abundant and complex post-translational modifications, with its importance underlined by the fact that it has an impact upon protein function. Aberrant glycosylation plays a pivotal role in a multitude of physiological states...
Biochem Soc Trans (2009) 37 (6): 1207–1213.
Published: 19 November 2009
... 2009 Biochemical Society 2009 angiogenesis carcinoma sample Denys–Drash syndrome human vitreous fluid rheumatoid arthritis vasculogenesis VEGF has become a centre of intense interest due to its essential role in neovascularization (vasculogenesis and angiogenesis) (for reviews see...
Biochem Soc Trans (2006) 34 (5): 727–730.
Published: 25 October 2006
...K.A. Reedquist; J. Ludikhuize; P.P. Tak Although the mechanisms leading to the induction of RA (rheumatoid arthritis) are poorly understood, improper activation, proliferation, survival and retention of neutrophils, macrophages, lymphocytes and other leucocytes contribute to perpetuation...
Biochem Soc Trans (2003) 31 (4): 770–773.
Published: 01 August 2003
... subjects with MBL deficiency remain healthy. MBL deficiency is also associated with non-infectious diseases including systemic lupus erythematosus, rheumatoid arthritis, cystic fibrosis and common variable immunodeficiency. MBL deficiency may affect susceptibility to (e.g. meningococcal disease), or alter...
Biochem Soc Trans (2002) 30 (6): 883–886.
Published: 01 November 2002
...S. Baig; Y. Patel; P. Coussons; R. Grant Erythropoietin (EPO), a haemopoietic growth factor and a primary regulator of erythropoiesis, is widely used to treat anaemia in various chronic complications of rheumatoid arthritis (RA). Fibro-blast-like cells, found in the pannus tissue of joints...